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Hepatitis caused by antidepressive therapy with maprotiline and opipramol.

Author: BergerM, BraunJ S, GeigerR, SchäfferS, WehnerH

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes severe acute hepatitis caused by maprotiline and opipramol in a patient with a history of unipolar depressive disorder. This case highlights the importance of considering hepatic side effects when using these antidepressants, particularly when clinical symptoms emerge.
Paper Details　
Original Abstract of the Article :
There are few published reports of antidepressive therapy induced hepatotoxicity. In most cases antidepressants cause only slight elevation of liver enzymes without clinical relevance. However, our patient with recidivation of unipolar depressive disorder developed severe laboratory abnormalities an...See full text at original site
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引用元：
https://doi.org/10.1055/s-2007-979319

データ提供：米国国立医学図書館（NLM）

Hepatitis Linked to Antidepressant Therapy: A Rare Case

This case report explores the rare occurrence of hepatitis, a liver inflammation, caused by antidepressant therapy. It's like finding a strange oasis in the desert, where the expected greenery is replaced with something unexpected. The authors report a case where a patient developed severe liver abnormalities and symptoms while taking maprotiline and opipramol, two commonly used antidepressants. The patient's symptoms resolved after stopping the medication, highlighting the potential for these drugs to cause severe adverse effects. This study underscores the importance of careful monitoring and prompt intervention when patients experience unexplained symptoms during antidepressant therapy.

The Need for Vigilance

This case report emphasizes the need for vigilance in monitoring patients taking maprotiline and opipramol. While these drugs can be effective in treating depression, it's important to be aware of the potential for severe side effects, like encountering a hidden sandstorm on your journey through the desert. This study serves as a reminder that even seemingly safe medications can have unexpected consequences.

Patient Safety First

This study highlights the importance of patient safety and the need for comprehensive monitoring during antidepressant therapy. Doctors and patients must work together to ensure that any potential side effects are identified and addressed promptly. This study is a reminder that even with the best intentions, unexpected challenges can arise in the healthcare journey. It is essential to be vigilant and ready to adapt to new information.

Dr. Camel's Conclusion

This case report serves as a cautionary tale, highlighting the potential for even seemingly safe medications to cause serious side effects. Like a wise traveler in the desert, doctors and patients must be aware of the potential risks and prepared to adapt their course when necessary. Patient safety should always be the top priority, and vigilance is essential when navigating the complexities of healthcare.

Date :
  1. Date Completed 1998-12-03
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

9754852

DOI: Digital Object Identifier

10.1055/s-2007-979319

Related Literature

Article Analysis
・Side Effects of maprotiline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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