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Long-term treatment of ulcerative colitis with ciprofloxacin: a prospective, double-blind, placebo-controlled study.

Author: FärkkiläM A, HakalaK, MiettinenT A, OgrenM, SeppäläK, SivonenA, TurunenU M, ValtonenV V, VuoristoM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the effectiveness of ciprofloxacin in treating ulcerative colitis, a chronic inflammatory bowel disease. While gut bacteria are thought to play a role in the development of ulcerative colitis, antibiotics are not currently a standard treatment. This study focused on patients whose symptoms were not adequately controlled by conventional medications like steroids and mesalamine, examining whether ciprofloxacin could help induce and maintain remission in these individuals.
Paper Details　
Original Abstract of the Article :
Although bacterial bowel flora may be one of the contributing factors in the pathogenesis of chronic mucosal inflammation, antibiotic treatment has no established role in ulcerative colitis. The aim of the study was to evaluate the role of ciprofloxacin in the induction and maintenance of remission ...See full text at original site
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引用元：
https://doi.org/10.1016/s0016-5085(98)70076-9

データ提供：米国国立医学図書館（NLM）

Ciprofloxacin: A Potential Weapon Against Ulcerative Colitis

Ulcerative colitis, a chronic inflammatory bowel disease, is a challenging condition, and its treatment remains an active area of research. This study examines the role of ciprofloxacin, an antibiotic, in inducing and maintaining remission in ulcerative colitis patients who have not responded well to conventional therapies.

Antibiotics in the Fight Against Ulcerative Colitis: Exploring a New Frontier

The authors explore the potential of ciprofloxacin as a therapeutic agent for ulcerative colitis. The study investigates the efficacy of ciprofloxacin in patients who have not achieved remission with traditional treatments, potentially opening up new avenues for managing this condition.

Harnessing the Power of Antibiotics: Potential Applications in Ulcerative Colitis Treatment

This research delves into the intricate relationship between bacterial flora and ulcerative colitis. The findings could pave the way for a more targeted approach to treating this condition, potentially improving the lives of patients living with ulcerative colitis.

Dr.Camel's Conclusion

This research is like discovering a hidden spring in the desert, offering a new source of hope for patients with ulcerative colitis. The study's findings suggest that ciprofloxacin could potentially be a valuable tool in the fight against this challenging disease.

Date :
  1. Date Completed 1998-11-30
  2. Date Revised 2019-07-07
Further Info :

Pubmed ID

9797360

DOI: Digital Object Identifier

10.1016/s0016-5085(98)70076-9

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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