[The effects of midazolam on oxygen consumption and the level of vigilance. The possibility of the sedative effect of the plexiglas dome (canopy) of the Deltatrac indirect calorimetry device].

Author: AuquierP, BruderN, DumontJ C, FrançoisG, KerbaulF

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To assess the effects of midazolam on oxygen consumption (VO2) and the level of vigilance. To search for a possible "sedative effect" of the canopy of the Deltatrac (Datex) when a placebo is administered instead of midazolam. STUDY DESIGN: Prospective, comparative, randomized, double-bli...See full text at original site
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引用元:
https://doi.org/10.1016/s0750-7658(00)80004-0

データ提供:米国国立医学図書館(NLM)

Measuring Oxygen Consumption: A Tale of Two Sedatives

Oxygen consumption is a vital indicator of our health, like a camel’s ability to navigate a sandstorm. This study explored the effects of midazolam, a sedative, on oxygen consumption and the level of vigilance, which is like measuring the camel's ability to stay alert and aware of its surroundings.

The study found that midazolam significantly decreased oxygen consumption in healthy volunteers, but there was no significant difference in oxygen consumption between the midazolam group and the placebo group. This is like a camel taking a rest under a shady tree, reducing its energy expenditure but not losing its ability to navigate the desert.

The Mystery of the Canopy

The study also investigated the potential sedative effect of a plexiglass dome used in the oxygen consumption measurement device. This is like trying to understand if the shade of a tree can induce drowsiness in a camel.

Staying Alert in the Desert

This research reminds us that understanding the effects of medication on both our physical and cognitive function is critical, especially when it comes to sedatives. It’s important to be aware of potential side effects and consult with a medical professional if you have any concerns. Like a camel navigating a sandstorm, we need to stay alert and aware of our surroundings.

Dr.Camel's Conclusion

This study highlights the intricacies of oxygen consumption and its relationship with sedation. It’s a reminder that even seemingly simple measurements can reveal complex and nuanced effects of medication on our bodies.

Date :
  1. Date Completed 1998-12-18
  2. Date Revised 2019-08-31
Further Info :

Pubmed ID

9835980

DOI: Digital Object Identifier

10.1016/s0750-7658(00)80004-0

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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