Paper Details 
Original Abstract of the Article :
Omeprazole 20mg once (od) or twice daily (bd), clarithromycin 250mg bd, and tinidazole 500 mg bd for 7 days (OCT) is an effective regimen against Helicobacter pylori, but the effect of 5-nitroimidazole resistance is unclear. We aimed to evaluate this using the disc diffusion technique and E-test to ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/9840021

データ提供:米国国立医学図書館(NLM)

Eradicating Helicobacter pylori: The Antibiotic Sensitivity Conundrum

The world of [gastroenterology] is constantly searching for ways to combat [Helicobacter pylori], a bacterium known to cause [gastric ulcers and other gastrointestinal problems]. This study explores the effectiveness of the triple therapy [OCT] regimen in eradicating [Helicobacter pylori] and investigates how [antibiotic sensitivity] plays a role in treatment success.

Antibiotic Sensitivity: A Key Determinant?

The study found that [OCT] was effective in eradicating [Helicobacter pylori] in a significant majority of patients. However, the researchers observed that [metronidazole resistance] did not necessarily predict treatment failure. While [metronidazole resistance] seemed to have a slight impact on eradication rates, the difference was not statistically significant. This suggests that other factors, perhaps [patient-specific factors], might be more important in determining treatment success.

The Quest for a Reliable Predictor

The study highlights the need for further research to identify reliable predictors of [OCT] failure. The findings suggest that [antibiotic sensitivity] alone may not be a sufficient predictor, and further investigation into other factors, such as [patient-specific factors], is warranted. This is like searching for a rare desert flower amidst a sea of sand - a challenge, but ultimately rewarding.

Dr.Camel's Conclusion

This study, like a lone camel navigating a vast desert, sheds light on the complex interplay between [antibiotic sensitivity] and treatment outcomes for [Helicobacter pylori] infections. The findings emphasize the need for a multifaceted approach to understanding the factors that influence treatment success. While [metronidazole resistance] may play a role, it's not the only factor to consider. This research paves the way for a more comprehensive understanding of [Helicobacter pylori] infections and the development of more effective treatment strategies.

Date :
  1. Date Completed 1999-02-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

9840021

DOI: Digital Object Identifier

9840021

Related Literature

SNS
PICO Info
in preparation
Languages

English

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