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The management of unexplained infertility.

Author: Abu-HeijaA, ZayedF

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Unexplained infertility, diagnosed after standard tests reveal no abnormalities, affects 6% to 60% of couples. While danazol and bromocriptine have shown no benefit, clomiphene citrate treatment can double the spontaneous pregnancy rate. Human menopausal gonadotropin (hMG) treatment yields a 2-26% pregnancy rate per cycle, lower than in vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT) rates (25-30%). A suggested treatment plan involves up to four cycles of clomiphene citrate with or without intrauterine insemination (IUI), followed by superovulation with hMG and IUI if needed. If these options are unsuccessful, assisted reproductive techniques (ART) should be considered.
Paper Details　
Original Abstract of the Article :
Unexplained infertility is a diagnosis made by exclusion after all of the standard investigations have revealed no abnormality (1). The range of the prevalence is from 6 to 60 percent (23), depending on the diagnostic criteria. This article reviews the literature in the management of unexplained inf...See full text at original site
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引用元：
https://doi.org/10.1097/00006254-199902000-00022

データ提供：米国国立医学図書館（NLM）

Unraveling the Mystery of Unexplained Infertility

The world of infertility is a vast and perplexing desert, often leaving couples feeling lost and alone. This research focuses on the challenging diagnosis of "unexplained infertility," where standard investigations fail to reveal any clear cause. The study delves into the existing literature, reviewing the effectiveness of various treatment options for couples facing this frustrating diagnosis. The researchers found that while some treatments, such as danazol and bromocriptine, showed no benefit, others, including clomiphene citrate and human menopausal gonadotrophin (hMG), demonstrated some success. The study also highlights the promising potential of assisted reproductive techniques (ART) such as in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT).

Hope on the Horizon: A Treatment Roadmap

This study provides a roadmap for couples struggling with unexplained infertility, offering a structured approach to treatment. The researchers recommend a combination of medication and assisted reproductive techniques, tailored to the individual needs of each couple. The study suggests that a combination of clomiphene citrate, intrauterine insemination (IUI), and, if necessary, ART procedures may offer the best chance of success. While the statistics may vary, the study provides a glimmer of hope for couples navigating this challenging journey.

A Camel's Guide to Fertility Treatment

Understanding the different treatment options for unexplained infertility is crucial for making informed decisions. The research emphasizes the importance of working closely with a healthcare provider to determine the most appropriate approach. This study offers valuable information for couples seeking to increase their chances of achieving a pregnancy. Remember, the desert of infertility can be daunting, but with the right guidance and support, a successful outcome is possible.

Dr.Camel's Conclusion

This research sheds light on the complexities of unexplained infertility, offering valuable insights into treatment options and success rates. It is a reminder that the journey to parenthood is not always straightforward. This study encourages couples to stay hopeful and seek the guidance of qualified healthcare professionals to navigate this challenging landscape.

Date :
  1. Date Completed 1999-05-13
  2. Date Revised 2019-10-24
Further Info :

Pubmed ID

9950004

DOI: Digital Object Identifier

10.1097/00006254-199902000-00022

Related Literature

Article Analysis
・Effective treatment of infertility
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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