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Initial multicenter experience with double nucleoside therapy for human immunodeficiency virus infection during pregnancy.
Author: AxelrodJ, DiVitoM M, ErnestJ M, HittiJ, LivingstonE, MoneyD M, RobbinsD, SilvermanN S, WattsD H
Original Abstract of the Article :
OBJECTIVE: To study maternal and neonatal effects of combination nucleoside analog therapy administered to human immunodeficiency virus (HIV)-infected pregnant women for maternal indications. METHODS: A multicenter, prospective observational study was undertaken at six perinatal centers in the Unit...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784818/
データ提供:米国国立医学図書館(NLM)
A Double Dose of Hope: Exploring Nucleoside Analog Therapy for HIV-Infected Pregnant Women
The world of medicine is always searching for new ways to help mothers and their little ones. This research delves into the realm of [HIV treatment] and explores the effectiveness of [double nucleoside therapy] for pregnant women living with HIV. The study, conducted across six medical centers in the United States and Canada, employed a [prospective observational approach] to gather data on [39 women] who received [combination nucleoside analog therapy]. This approach allowed researchers to observe the therapy's effects on both mothers and their babies in a real-world setting.
Safe and Effective: A Glimpse into the Future of HIV Treatment
The findings are quite encouraging. The therapy proved to be well-tolerated by both mothers and their newborns, without any significant short-term toxicities or side effects. This is a crucial step forward in [HIV treatment] as it indicates a potential path toward safer and more effective treatment options. The study further revealed a [2.5% rate of neonatal HIV infection], which is promising considering the challenges associated with the disease.
A Mother's Love: Considerations for Newborns
While the results are positive, the study also highlights the importance of [close monitoring] of newborns' hematologic and liver function. This emphasizes the need for [ongoing research and clinical observation] to ensure the long-term safety and efficacy of this therapy.
Dr.Camel's Conclusion
This study offers a ray of hope for pregnant women living with HIV, indicating the potential for [double nucleoside therapy] to be a safe and effective treatment option. It's important to remember that [continuous monitoring and further research] are crucial for understanding the long-term effects of this therapy. Just like a camel navigating a vast desert, we must continue our journey of exploration in the world of medicine, seeking out new and innovative approaches to treat and prevent disease.
Date :
- Date Completed 1999-04-16
- Date Revised 2020-02-19
Further Info :
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