Side Effects of aloe vera: A Synthesis of Findings from 8 Studies

  1. Home
  2. Side Effects of aloe vera
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Side Effects of aloe vera: A Synthesis of Findings from 8 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Side Effects of aloe vera: A Synthesis of Findings from 8 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Main Research Findings

Aloe vera has shown promising effects in various studies, including wound healing , reducing skin irritation from chemotherapy , managing diabetes , treating periodontal disease 8 , alleviating allergies , and mitigating skin side effects from radiation therapy . However, these benefits are accompanied by potential side effects.

Reason for Side Effects

The presence of various components in aloe vera, including anthraquinones, can lead to side effects. Anthraquinones found in aloe vera leaves are known to potentially cause digestive issues like diarrhea and abdominal pain.

Common Side Effects

Diarrhea

Consuming aloe vera can lead to diarrhea, a common digestive symptom.

Abdominal Pain

Aloe vera consumption can also cause abdominal pain, another digestive issue.

Skin Inflammation

Applying aloe vera topically to the skin can cause skin inflammation. 2

Allergies

It's important to note that aloe vera can trigger allergic reactions in some individuals.

Countermeasures Against Side Effects

Diarrhea

If you choose to use aloe vera, start with small doses. If diarrhea persists, discontinue use and consult your doctor.

Abdominal Pain

When using aloe vera, begin with small amounts. If abdominal pain continues, stop using aloe vera and seek medical advice.

Skin Inflammation

Before applying aloe vera to your skin, test a small amount on a patch of your inner arm and observe for 24 hours. If no inflammation occurs, it is likely safe for use. If inflammation develops, discontinue use and consult your doctor.

Allergies

If you have a known allergy to aloe vera, avoid using it. If you experience any allergic reactions, consult your doctor.

Comparison Between Studies

Common Points in Studies

Multiple studies consistently highlight that aloe vera offers potential medicinal benefits while also emphasizing the possibility of side effects.

Differences in Studies

The specific side effects associated with aloe vera and their frequency can vary across studies. This variation may be attributed to factors such as the aloe vera variety, extraction methods, dosage, and individual sensitivity.

Precautions for Application in Daily Life

While aloe vera has various applications, it's crucial to understand its potential side effects before using it. Pregnant women, breastfeeding mothers, and individuals with existing health conditions should consult their doctor before using aloe vera products.

Limitations of Current Research

Current research on aloe vera side effects is still limited. More extensive research is needed, particularly regarding long-term side effects and specific side effects in relation to different diseases.

Future Research Directions

Given the potential benefits and risks of aloe vera, further research is crucial. Focus should be placed on long-term side effects, specific side effects related to various health conditions, and identifying safe and effective methods of use.

Conclusion

Aloe vera offers promising benefits for various health issues. However, the possibility of side effects should be acknowledged. When using aloe vera, it is essential to be informed about potential risks and utilize it responsibly. Further research is needed to better understand the long-term effects and potential side effects related to specific diseases.

Literature analysis of 8 papers
Positive Content
6
Neutral Content
0
Negative Content
2
Article Type
1
0
0
0
8
1.

The Effects of Aloe Vera on TNF-a Levels, the Percentage of Nk Cells and Th 17 Cells in Rat That Received Izoniazid and Rifampycin.

Author: MawartiHerin, RajinMukhamad, AsumtaZulfikar

None mentioned
Liver damage

The study found that administration of

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

2.

Aloe Vera-Containing Matrix in Transdermal Fentanyl Therapy Improves Adhesion, Skin Tolerance and Quality of Life: Results of a German Multicenter Study with a New Fentanyl Patch.

Author: DietrichChristoph G, KottmannTanja, VoßHans Werner, LorenzRoxane

Improved sleep
Reduced pain
Poor adhesion
Skin irritation

This study investigated the effectiveness of transdermal opioid therapy for chronic pain in older adults. It found that patches with a lower adhesive strength were associated with reduced skin irritation and increased patient satisfaction compared to patches with a higher adhesive strength. However, it did not analyze pain reduction as an outcome measure.

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

4.

Effect of daily drinking of Aloe vera gel extract on plasma total antioxidant capacity and oral pathogenic bacteria in healthy volunteer: a short-term study.

Author: PrueksrisakulTitipong, ChantarangsuSoranun, ThunyakitpisalPasutha

Increased TAC
Reduced Lactobacillus spp.

Aloe vera gel extract significantly increased plasma total antioxidant capacity and decreased the number of Lactobacillus spp. without any clinical side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

5.

Tes, Licuados, and Capsulas: herbal self-care remedies of Latino/Hispanic immigrants for type 2 diabetes.

Author: AmirehsaniKaren A, WallaceDebra C

Herbal remedy use

A majority of Latino/Hispanic adults with type 2 diabetes reported using herbal remedies for diabetes self-care. Most did not disclose their use to health care providers.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

A randomized clinical study for comparative evaluation of Aloe Vera and 0.2% chlorhexidine gluconate mouthwash efficacy on de-novo plaque formation.

Author: ChhinaShivjot, SinghAvnish, MenonIpseeta, SinghRickypal, SharmaAnubhav, AggarwalVartika

Antiplaque efficacy

Aloe vera mouthwash is as effective as 0.2% chlorhexidine gluconate mouthwash in reducing plaque formation.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

7.

Efficacy of adjunctive therapy using Vizoovet in improving clinical signs of keratoconjunctivitis sicca in dogs: A pilot study.

Author: DeesD Dustin, KentMichael S

KCS treatment

Adjunctive treatment with Vizoovet was as safe and effective as GenTeal drops in improving clinical signs of dry eye in dogs.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled Trial, VeterinaryRandomized controlled trials involving animals. They evaluate the efficacy and safety of treatment methods.

Language : English

8.

Clinical Efficacy of Aloe Vera Toothpaste on Periodontal Parameters of Patients with Gingivitis-A Randomized, Controlled, Single-masked Clinical Trial.

Author: SayarFerena, FarahmandAmir H, RezazadehMaryam

Gingivitis treatment

Aloe vera toothpaste showed no significant improvement in dental plaque and gingivitis compared to fluoride toothpaste, suggesting it can be used as an alternative.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.