Effective treatment of breathing problems: A Synthesis of Findings from 22 Studies

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Original Abstract of the Article

Major Research Findings

Breathing problems can be caused by a variety of factors, and effective treatments vary depending on the cause. For example, the study 9 found that it is unclear which treatment is best for children with neurodisabilities who have chronic pulmonary infections. Meanwhile, the study 16 evaluated the effects of an intermittent aerobic training program on children with cerebral palsy and asthma. Furthermore, 15 suggested the potential of computational fluid dynamics models to enable individualized surgical treatment for nasal obstruction. These studies provide valuable insights into the development of breathing problem treatments, but further research is needed.

Treatment Summary

The study 9 found that it is unclear which treatment is best for children with neurodisabilities who have chronic pulmonary infections. Therefore, the development of more effective treatments is needed.

The study 16 suggests that an aerobic training program may be effective for children with cerebral palsy and asthma. However, this study was small and needs further investigation.

The study 15 suggested the potential of computational fluid dynamics models to enable individualized surgical treatment for nasal obstruction. This model could potentially help to create more precise treatment plans, but further research is needed before it can be used in clinical settings.

Benefits and Risks

Benefit Summary

Treatments for breathing problems vary depending on the cause. For example, an aerobic training program may help improve exercise capacity and lung function in children with cerebral palsy and asthma. 16 . Furthermore, computational fluid dynamics models may be useful for creating individualized surgical treatment plans for nasal obstruction. 15 .

Risk Summary

Each treatment for breathing problems has associated risks. An aerobic training program could be too strenuous for some children. 16 . Additionally, computational fluid dynamics models are still in the research stage, and caution should be exercised when using them in clinical settings. 15 .

Comparison of Studies

Similarities in Studies

These studies all contribute valuable insights into the development of treatments for breathing problems.

Differences in Studies

These studies focus on different diseases and treatments, making direct comparisons difficult. However, each study provides important information that can contribute to the development of treatments for breathing problems.

Consistency and Discrepancies in Results

The results of these studies do not always consistently demonstrate the effectiveness of treatment for breathing problems. For example, the study 9 found that it is unclear which treatment is best for children with neurodisabilities who have chronic pulmonary infections. On the other hand, the study 16 suggests that an aerobic training program may be effective for children with cerebral palsy and asthma. Thus, the effectiveness of treatment for the same disease can vary between different studies. Further research is therefore needed.

Cautionary Notes Regarding Application in Real Life

It is important to be cautious when applying the results of these studies in real life. For example, an aerobic training program could be too strenuous for some children. 16 . Furthermore, computational fluid dynamics models are still in the research stage, and caution should be exercised when using them in clinical settings. 15 . Therefore, it is crucial to consult with a doctor when choosing a treatment for breathing problems.

Limitations of Current Research

These studies are all relatively small and need further investigation. Furthermore, they focus on a limited number of diseases and treatments, so they may not apply to all breathing problems.

Future Research Directions

Further research is needed to develop treatments for breathing problems. In particular, studies are needed that compare the effectiveness of different treatments for different diseases. Additionally, guidelines for applying research findings to real-life situations are needed.

Conclusion

Breathing problems can be caused by a variety of factors. Effective treatments vary depending on the cause. While these studies provide valuable insights into the development of treatments for breathing problems, further research is needed. It is important to consult with a doctor when choosing a treatment for breathing problems.

List of Treatments

Aerobic training program, computational fluid dynamics model, 7 (betamimetics, systemic corticosteroids), 2 (orthognathic surgery), 18 (AdvanSync2 Class II corrector), 8 (YPL-001), 19 (Nilavembu Kudineer)

Literature analysis of 22 papers
Positive Content
16
Neutral Content
2
Negative Content
4
Article Type
1
0
1
5
20
3.

Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem.

Author: SabooKeyur, GemnaniRinkle R, ManujaNishtha, KumarSunil, AcharyaSourya

Neonatal goiter

A newborn presented with goiter caused by maternal exposure to propylthiouracil (PTU) during pregnancy. This case highlights the importance of careful thyroid function monitoring in newborns exposed to PTU and raises questions about PTU's suitability as first-line treatment for maternal Graves' disease.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Language : English

5.

Family-Reflections.com: Creating a parent-to-parent web-based tool regarding pediatric home ventilation.

Author: VoHolly Hoa, WilfondBenjamin S, DingYuanyuan, HendersonCarrie M, RaisanenJessica C, AshwalGary, ThomasAlex, JabreNicholas A, ShipmanKelly J, SchrootenAnn, ShafferJennifer, BossRenee D

Home ventilation

Parents of children requiring tracheostomy and home ventilation often seek information from other parents who have faced similar decisions. This study explores the challenges of parent-to-parent communication and highlights the need for effective mechanisms to connect families for informed decision-making.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

Therapy Outcomes for Teenage Athletes With Exercise-Induced Laryngeal Obstruction.

Author: FujikiRobert Brinton, Olson-GrebBryn, BradenMaia, ThibeaultSusan L

Decreased dyspnea
Improved activity participation

Speech-language pathology intervention for exercise-induced laryngeal obstruction (EILO) in teenage athletes showed significant improvements in breathing problems, activity participation, and inhaler use. In a prospective cohort study, patients reported more frequent and complete activity participation immediately post-therapy and decreased dyspnea symptoms 6 months post-therapy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

7.

Severe bronchiolitis profiling as the first step towards prevention of asthma.

Author: OrzołekIzabela, AmbrożejDominika, MakriniotiHeidi, ZhuZhaozhong, JarttiTuomas, FeleszkoWojciech

Asthma prevention
Bronchiolitis
Severe bronchiolitis

Bronchiolitis is a common respiratory infection in infants, with rhinovirus (RV) and respiratory syncytial virus (RSV) being the main culprits. This study highlights the need for a more individualized approach to bronchiolitis treatment, considering different viral etiologies, atopic status, and risk factors for future asthma development.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

9.

Antibiotics for chronic pulmonary infection in children with a neurodisability (neurodevelopmental disorder).

Author: SannerJuliane Rf, JainKamini, WilliamsJane, HurleyMatthew N

Airway clearance
Neurodisability
Pulmonary infections

Children and young people with neurodisabilities often experience chest and breathing problems, including pulmonary infections, leading to frequent hospitalizations. The lack of clear treatment guidelines for chronic pulmonary infections in this population highlights the need for further research.

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

11.

Bilateral collagenous fibroma of the hard palate: a case report and review of the literature.

Author: El-NaggarHagar A, El-MahallawyYehia A, HarbyMohamed I, Abou MadawiNourhan A

Diagnosis
Tumor management

This case report describes a rare case of bilateral collagenous fibroma on the hard palate and discusses its management and diagnosis.

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

13.

Anaphylaxis in Risky Populations.

Author: BeyazŞengül, GelincikAslı

Improved anaphylaxis management

This review discusses the challenges of diagnosing and managing anaphylaxis, a serious allergic reaction. The review highlights risk factors for severe anaphylaxis and the need for a precision medicine approach to treatment.

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

14.

Study protocol for a revised randomized trial: Remotely delivered Tai Chi and wellness for Gulf War illness.

Author: NilesBarbara L, GrossmanStephanie, McQuadeMaria, GrossmanDaniel, KaiserAnica Pless, MuccioBrian, WarnerBen, WangChenchen, MoriDeAnna L

Improved mental health
Improved physical health
Improved quality of life

This study explored the potential benefits of Tai Chi as a treatment for Gulf War Illness, a cluster of health symptoms reported by military personnel deployed to the Persian Gulf region in 1990 and 1991. The study aimed to find evidence-based support for Tai Chi as a complementary therapy for managing chronic conditions associated with Gulf War Illness.

Clinical Trial ProtocolA plan for conducting a clinical trial. It describes in detail the purpose, design, methodology, and statistical considerations of the trial, ensuring the transparency and consistency of the trial.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Language : English

15.

Computational Fluid Dynamics Could Enable Individualized Surgical Treatment of Nasal Obstruction (A Preliminary Study).

Author: PlášekMarek, MasárováMichaela, BojkoMarián, KomínekPavel, MatoušekPetr, FormánekMartin

Nasal Disorder Diagnosis
Personalized Surgery

This study developed a computational fluid dynamics (CFD) model of nasal airflow to help with individualized surgical planning for nasal disorders by determining the main routes of airflow through the nasal cavity.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

16.

Effects of intermittent aerobic training on exercise capacity, pulmonary functions, and gait parameters in asthmatic children with cerebral palsy: a randomized controlled trial.

Author: SolimanG S, AzabA R, AbdelbassetW K

CP exercise
Asthmatic CP

This study evaluated the effects of intermittent aerobic training on exercise capacity, pulmonary function, and gait parameters in asthmatic children with cerebral palsy (CP). The study aimed to investigate the potential benefits of exercise training for improving physical function and overall well-being in this population.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

17.

Rapid Maxillary Expansion (RME): An Otolaryngologic Perspective.

Author: CerritelliLuca, HatzopoulosStavros, CatalanoAndrea, BianchiniChiara, CammarotoGiovanni, MeccarielloGiuseppe, IannellaGiannicola, ViciniClaudio, PelucchiStefano, SkarzynskiPiotr Henryk, CiorbaAndrea

Hearing loss
Nasal function
OSA treatment

This review article examines the potential otolaryngological benefits of rapid maxillary expansion (RME) in children. RME has been shown to improve nasal breathing, reduce ear infections, and potentially alleviate obstructive sleep apnea. The study highlights the importance of otolaryngologists considering RME as a treatment option.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

19.

Evaluation of the active constituents of Nilavembu Kudineer for viral replication inhibition against SARS-CoV-2: An approach to targeting RNA-dependent RNA polymerase (RdRp).

Author: KuriakoseAnisha, NairBhagyalakshmi, AbdelgawadMohamed A, AdewumAdeniyi T, SolimanMahmoud E S, MathewBijo, NathLekshmi R

COVID-19 treatment

Phytochemicals from Nilavembu Kudineer, a traditional Siddha formulation, show potential for treating COVID-19 by inhibiting the viral RNA-Dependent RNA Polymerase (RdRp) enzyme.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

20.

Differences between adults who smoke cigarettes daily and do and do not co-use cannabis: Findings from the 2020 ITC four country smoking and vaping survey.

Author: GravelyShannon, DriezenPete, McClureErin A, HammondDavid, Michael CummingsK, ChanGary, HylandAndrew, BorlandRon, EastKatherine A, FongGeoffrey T, SchauerGillian L, QuahAnne C K, OuimetJanine, SmithDanielle M

Cannabis use

This study investigated population-level differences between adults who exclusively smoke cigarettes and those who smoke cigarettes and also use cannabis. The study aimed to identify sociodemographic, cigarette dependence, health, behavioral, and risk perception differences between the two groups.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

21.

Disease burden in individuals with symptomatic undiagnosed asthma or COPD.

Author: AlhabeebFatmah F, WhitmoreG A, VandemheenKatherine L, FitzGeraldJ Mark, BergeronCeline, LemièreCatherine, BouletLouis-Philippe, FieldStephen K, PenzErika, McIvorR Andrew, GuptaSamir, MayersIrvin, BhutaniMohit, HernandezPaul, LougheedDiane, LicskaiChristopher J, AzherTanweer, CoteAndreanne, AinslieMartha, FraserIan, MahdavianMasoud, AaronShawn D

COPD and asthma diagnosis
Undiagnosed respiratory symptoms

COPD and asthma may be underdiagnosed. This study compares health care utilization, symptoms, and quality of life in individuals with self-reported respiratory symptoms who were found to have undiagnosed airflow obstruction versus those without airflow obstruction.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

22.

The Hydroalcoholic Extract of <i>Nasturtium officinale</i> Reduces Lung Inflammation and Oxidative Stress in an Ovalbumin-Induced Rat Model of Asthma.

Author: ShakerinasabNasrin, BejeshkMohammad Abbas, PourghadamyariHossein, NajafipourHamid, EftekhariMahdieh, MottaghipishehJavad, OmidifarNavid, AziziMahdokht, RajizadehMohammad Amin, DoustimotlaghAmir Hossein

Anti-inflammation
Antioxidant
Asthma

<i>Nasturtium officinale</i> (<i>NO</i>) has anti-inflammatory and antioxidant properties and may help treat asthma. This study investigated the effects of <i>NO</i> extract in a rat model of asthma.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

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