Side Effects of iloprost: A Synthesis of Findings from 30 Studies
- Home
- Side Effects of iloprost
This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Side Effects of iloprost: A Synthesis of Findings from 30 Studies", please consult your doctor.
For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
Major Research Findings
Iloprost is a prostacyclin analog used to treat pulmonary arterial hypertension (PAH) and has been shown to improve exercise capacity and quality of life in patients with PAH. 11 Iloprost can also be used to treat pulmonary hypertension in newborns, particularly in cases where inhaled nitric oxide (iNO) is unavailable. 29 Iloprost has also been investigated for the treatment of Raynaud's phenomenon and digital ulcers associated with systemic sclerosis, although side effects are a concern in this population. 21
Reasons for Side Effects
The side effects of iloprost are primarily attributed to its vasodilatory action, as it is a prostacyclin analog. 10 These side effects can also vary depending on the method and dosage of administration. 18
Common Side Effects
Headache
Headache is a common side effect of iloprost and is often linked to its vasodilatory action. 5
Flushing
Flushing, a reddening of the skin, is another common side effect of iloprost, likely caused by its vasodilatory effect. 23
Diarrhea
Diarrhea is a potential side effect of iloprost, possibly due to its effects on the gastrointestinal tract. 21
Hypotension
Hypotension, or low blood pressure, is a risk with iloprost administration, likely due to its vasodilatory action. 21
Tachycardia
Tachycardia, or rapid heart rate, is another possible side effect of iloprost, often linked to its vasodilatory properties. 23
Atrial Fibrillation
Atrial fibrillation, an irregular heart rhythm, has been observed as a potential side effect of iloprost. 23
Gastrointestinal Symptoms
Iloprost can also cause gastrointestinal symptoms such as nausea and vomiting. 9
Countermeasures for Side Effects
Headache
Headache from iloprost can often be alleviated by reducing the dosage. 21 Over-the-counter pain relievers may also provide relief. 21
Flushing
Flushing can be managed by decreasing the dose of iloprost or by using cool compresses. 21
Diarrhea
Diarrhea related to iloprost can often be managed by dose reduction. 21 Antidiarrheal medications may also be helpful. 21
Hypotension
Hypotension from iloprost may be addressed by lowering the dosage. 21 Increasing salt intake can also help. 21
Tachycardia
Tachycardia from iloprost might be reduced by lowering the dose. 21 Beta-blockers might also be helpful. 21
Atrial Fibrillation
If atrial fibrillation is caused by iloprost, the medication may need to be discontinued. 21
Comparison between Studies
Common Points of Research
Multiple studies have found that iloprost is effective in treating pulmonary arterial hypertension (PAH). 10 Several studies also indicate that iloprost can cause side effects such as headache, flushing, diarrhea, and hypotension. 21
Differences in Research
The prevalence and severity of side effects from iloprost can vary between studies. 21 For instance, one study reported common side effects, while another study found a lower incidence of these effects. 23 These differences likely reflect variations in patient populations, dosages, and other factors. 21
Points to Note Regarding Application to Real Life
Iloprost is an effective treatment for conditions like pulmonary arterial hypertension (PAH), but it's important to be aware of the potential for side effects. 10 Always follow your doctor's instructions and take the correct dosage when using iloprost. 10 If you experience side effects like headache, flushing, diarrhea, or low blood pressure, contact your doctor immediately. 21
Limitations of Current Research
There is still limited research on the side effects of iloprost. 21 The long-term effects, in particular, remain understudied. 21
Future Research Directions Needed
Further investigation into the side effects of iloprost is crucial. 21 Research evaluating long-term side effects is particularly important. 21 Additionally, research into methods to minimize or mitigate these side effects is needed. 21
Conclusion
Iloprost is a potentially effective drug for various conditions like pulmonary arterial hypertension (PAH), but it's essential to recognize the potential for side effects. 10 Always adhere to your doctor's instructions regarding dosage and usage. 10 If you experience any side effects while taking iloprost, promptly consult your doctor. 21
Benefit Keywords
Risk Keywords
Article Type
Author: ParamothayanN S, LassersonT J, WellsA U, WaltersE H
Language : English
Author: MeloniMichele, TorrazzaMario, LeddaRoberto
Language : English
Author: WilhelmW, GrundmannU
Language : German
Author: MardlaVilja, KobzarGennadi, SamelNigulas
Language : English
Author: BaysalAyse, BilselSerpil, BulbulOzlem Gumustekin, KayaciogluIlyas, IdizMustafa, YekelerIbrahim
Language : English
Author: GesslerTobias, SeegerWerner, SchmehlThomas
Language : English
Author: KrugSabine, SablotzkiArmin, HammerschmidtStefan, WirtzHubert, SeyfarthHans-Juergen
Language : English
Author: WinterhalterMichael, AntoniouTheofani, LoukanovTsvetomir
Language : English
Author: MorrisonKeith, ErnstRoland, HessPatrick, StuderRolf, ClozelMartine
Language : English
Author: GuptaVivek, AhsanFakhrul
Language : English
Author: EwertRalf, GläserSven, BollmannTom, SchäperChristoph
Language : English
Author: BlaiseSophie, RoustitMatthieu, HellmannMarcin, MilletClaire, CracowskiJean-Luc
Language : English
Author: ElkiranOzlem, KarakurtCemşit, KoçakGülendam
Language : English
Author: CeliaChristian, LocatelliMarcello, CilurzoFelisa, CoscoDonato, GentileEmanuela, ScaliseDaniela, CarafaMaria, VenturaCinzia Anna, FleuryMathias, TisserandChristelle, BarbacaneRenato C, FrestaMassimo, Di MarzioLuisa, PaolinoDonatella
Language : English
Author: ThunbergC A, MorozowichS T, RamakrishnaHarish
Language : English
Author: NingNing, WangLan, ZhangHongda, LiuQianqian, PengFuhua, ZhaoQinhua, JiangXin, HeJing, JiangRong, JingZhicheng
Language : Chinese
Author: TruseRichard, HinterbergJonas, SchulzJan, HerminghausAnna, WeberAndreas, Mettler-AltmannTabea, BauerInge, PickerOlaf, VollmerChristian
Language : English
Author: UnalSezin, AktasSelma, AksuMeltem, HirfanogluIbrahim M, AtalayYildiz, TurkyilmazCanan
Language : English
A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension.
Author: TheodorakiKassiani, ThanopoulosApostolos, RelliaPanagiota, LeontiadisEvangelos, ZarkalisDimitrios, PerreasKonstantinos, AntoniouTheophani
Language : English
Author: FraticelliPaolo, MartinoGiuseppe Pio, MurriMarta, MattioliMassimo, GabrielliArmando
Language : English
Author: Bellando-RandoneS, BruniC, LepriG, FioriG, BartoliF, ConfortiM L, Moggi-PignoneA, GuiducciS, GiuggioliD, ColaciM, SpinellaA, FerriC, Matucci-CerinicM
Language : English
Author: CacioneDaniel G, MacedoCristiane R, do Carmo NovaesFrederico, Baptista-SilvaJose Cc
Language : English
Author: TosunHacı Bayram, UludağAbuzer, DemirSukru, SerbestSancar, YasarMehmet Mete, ÖznamKadir
Language : English
Author: RobertsMaxine J, MayLauren T, KeenAlastair C, LiuBonan, LamTerrance, CharltonSteven J, RosethorneElizabeth M, HallsMichelle L
Language : English
Author: Fartura Braga TemidoMaria Helena, GomesManuel, ParenteFrancisco, SantosLèlita
Language : English
Author: MartinsPatrícia, DouradoEduardo, FonsecaJoão Eurico, RomãoVasco, ResendeCatarina
Language : English
Author: El-KershKarim, JalilBilal A
Language : English
Author: BobhatePrashant, GuptaRajat Kumar, KarandeTanuja, KulkarniSnehal
Language : English
Author: YıldırımŞükran
Language : English
Cyclooxygenase-2 inhibition prevents renal toxicity but not hypertension during sunitinib treatment.
Author: van DorstDaan C H, Mirabito ColafellaKatrina M, van VeghelRichard, GarreldsIngrid M, de VriesRené, MathijssenRon H J, DanserA H Jan, VersmissenJorie
Language : English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.