Causes of pregnancy and opioids: A Synthesis of Findings from 5 Studies

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Original Abstract of the Article

Key Findings

Opioid use during pregnancy is a major public health concern that can have serious consequences for both the mother and the baby. . These consequences include neonatal abstinence syndrome (NAS), low birth weight, preterm birth, and death. 2 . Opioid use during pregnancy can also affect the neurodevelopment of the baby. . Opioid use during pregnancy can also affect the health of the mother. 4 . Mothers with opioid addiction are at increased risk of death from opioid overdose. 4 . Mothers with opioid addiction may have difficulty accessing prenatal care. . Healthcare providers need to improve their knowledge and understanding of opioid use during pregnancy. .

Reasons for the Causes

Opioid use during pregnancy can cause many health problems for both the mother and the baby. The causes of these problems are that opioids can cross the placenta and affect fetal growth and development. . Opioids can affect the development of the fetal nervous system, respiratory system, and immune system, leading to problems such as neonatal abstinence syndrome (NAS). . Opioids can also affect the health of the mother, making it difficult to access prenatal care. . Mothers with opioid addiction are also at increased risk of death from opioid overdose. 4 .

Common Causes

Opioid Addiction

Opioid addiction is the most common cause of opioid use during pregnancy. . Mothers with opioid addiction are more likely to continue using opioids during pregnancy, which can affect the growth and development of the fetus. . Mothers with opioid addiction may also have difficulty accessing prenatal care. . Mothers with opioid addiction are also at increased risk of death from opioid overdose. 4 .

Access to Prenatal Care

Lack of access to prenatal care is another major cause of opioid use during pregnancy. . Mothers with opioid addiction are more likely to have difficulty accessing prenatal care, which can increase their risk of opioid use during pregnancy. . Healthcare providers need to improve their knowledge and understanding of opioid use during pregnancy. .

Solutions for the Causes

Treatment for Opioid Addiction

Mothers with opioid addiction need to be treated for their opioid addiction. . Opioid substitution therapy, such as methadone or buprenorphine, is used for mothers with opioid addiction during pregnancy. . These treatments can help reduce a mother’s dependence on opioids and reduce the risks to the fetus. .

Improving Access to Prenatal Care

Mothers with opioid addiction may have difficulty accessing prenatal care. . Mothers with opioid addiction need support to improve their access to prenatal care. . Healthcare providers need to improve their knowledge and understanding of opioid use during pregnancy. .

Comparison of Studies

Similarities of Studies

Opioid use during pregnancy can have serious consequences for both the mother and the baby. . Many studies show that opioid use during pregnancy increases the risk of neonatal abstinence syndrome (NAS), low birth weight, preterm birth, and death. 2 . Opioid use during pregnancy can also affect the neurodevelopment of the baby. . Opioid use during pregnancy can also affect the health of the mother. 4 .

Differences of Studies

Some studies show different levels of risk associated with opioid use during pregnancy. 2 . This may be due to many factors, such as the type of opioid used in the study, the age and health of the women studied, and the location where the study was conducted. 2 . In addition, factors such as treatment for opioid addiction and access to prenatal care can also affect the risk of opioid use during pregnancy. .

Implications for Real Life

Opioid use during pregnancy can have serious consequences for both the mother and the baby. . Mothers with opioid addiction need support to improve their access to prenatal care. . Healthcare providers need to improve their knowledge and understanding of opioid use during pregnancy. . The best way to avoid opioid use during pregnancy is to avoid opioid use altogether. .

Limitations of Current Research

There is still much research that needs to be done on opioid use during pregnancy. . Many studies are small and focus on specific types of opioids or specific populations. 2 . Furthermore, many studies on opioid use during pregnancy do not account for various factors. 2 . For example, factors such as treatment for opioid addiction and access to prenatal care, which can affect the risk of opioid use during pregnancy. .

Future Research Directions

More research is needed on opioid use during pregnancy. . Specifically, research that considers various factors that can affect the risk of opioid use during pregnancy is needed. 2 . For example, factors such as treatment for opioid addiction and access to prenatal care. . Also, further research is needed to understand how opioid use during pregnancy affects the long-term development of the baby. .

Conclusion

Opioid use during pregnancy can have serious consequences for both the mother and the baby. . Mothers with opioid addiction need support to improve their access to prenatal care. . Healthcare providers need to improve their knowledge and understanding of opioid use during pregnancy. . The best way to avoid opioid use during pregnancy is to avoid opioid use altogether. .

Literature analysis of 5 papers
Positive Content
3
Neutral Content
2
Negative Content
0
Article Type
0
0
2
0
5
1.

Comorbidities in polymyalgia rheumatica: a systematic review.

Author: PartingtonRichard, HelliwellToby, MullerSara, Abdul SultanAlyshah, MallenChristian

This study systematically reviews the literature on comorbidities associated with polymyalgia rheumatica (PMR), a common inflammatory rheumatological condition affecting older people.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

2.

Excess mortality in children born to opioid-addicted parents: A national register study in Taiwan.

Author: FangShao-You, HuangNicole, TsayJen-Huoy, ChangSu-Hui, ChenChuan-Yu

Methadone treatment
Reduced risk of death
Premature death

Children born to opioid-involved parents are at an increased risk of premature death, especially from unnatural causes. Low birth weight and paternal opioid problem severity are the most significant predictors of premature death.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

3.

Lysophosphatidic acid is a potential mediator of cholestatic pruritus.

Author: KremerAndreas E, MartensJob J W W, KulikWim, RuëffFranziska, KuiperEdith M M, van BuurenHenk R, van ErpecumKarel J, KondrackieneJurate, PrietoJesus, RustChristian, GeenesVictoria L, WilliamsonCatherine, MoolenaarWouter H, BeuersUlrich, Oude ElferinkRonald P J

Pruritus treatment

Lysophosphatidic acid (LPA) and autotaxin may play a critical role in cholestatic pruritus and may serve as potential targets for future therapeutic interventions. This study found that LPA concentrations were increased in cholestatic patients with pruritus and that autotaxin activity correlated with intensity of pruritus.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

4.

Postpartum Opioid-Related Mortality in Patients With Public Insurance.

Author: SuarezElizabeth A, HuybrechtsKrista F, StraubLoreen, Hernández-DíazSonia, CreangaAndreea A, ConneryHilary S, GrayKathryn J, VineSeanna M, JonesHendrée E, BatemanBrian T

Opioid use disorder treatment
Postpartum death
Postpartum opioid overdose

A cohort study of 4,972,061 deliveries in the United States found that the incidence of postpartum opioid overdose death was significantly higher among individuals with opioid use disorder (OUD) compared to all individuals. Postpartum use of medication to treat OUD was associated with a 60% lower risk of opioid overdose death.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

5.

Screening for Unhealthy Drug Use: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

Author: PatnodeCarrie D, PerdueLeslie A, RushkinMegan, DanaTracy, BlazinaIan, BougatsosChristina, GrusingSara, O'ConnorElizabeth A, FuRongwei, ChouRoger

Reduced drug use

This systematic review examined the literature on screening and interventions for drug use. Several screening instruments with acceptable sensitivity and specificity are available, but there is no direct evidence on the benefits or harms of screening. Psychosocial interventions were found to increase the likelihood of drug use abstinence and reduce drug use days. Opioid agonist therapy and naltrexone were effective in reducing drug use relapse in treatment-seeking populations.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

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