Side Effects of tretinoin topical: A Synthesis of Findings from 2 Studies

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Original Abstract of the Article

Major Research Findings

Tretinoin topical is an effective medication for treating various skin conditions such as solar lentigines and acne vulgaris. 2 found that tretinoin topical is effective in treating solar lentigines. 1 found that vitamin E did not reduce the side effects of isotretinoin when used in combination for treating acne vulgaris.

Reasons for side effects

Tretinoin topical works by increasing cell turnover in the skin. This can cause the skin to become thinner and more sensitive. Tretinoin topical can also make the skin more sensitive to sunlight. For this reason, it is important to wear sunscreen and avoid prolonged sun exposure when using tretinoin topical.

Common side effects

Dryness

Tretinoin topical can cause dryness of the skin. 1 found that isotretinoin can lead to side effects like dry eyes and lips.

Redness

Tretinoin topical can cause redness of the skin.

Itching

Tretinoin topical can cause itching of the skin.

Peeling

Tretinoin topical can cause peeling of the skin.

Photosensitivity

Tretinoin topical can make the skin more sensitive to sunlight.

Side effects management

Dryness

To manage dryness, apply a moisturizer to the skin regularly.

Redness

To manage redness, use a gentle cleanser and moisturizer. Consult a doctor if the redness is severe.

Itching

To manage itching, apply an anti-itch cream. Consult a doctor if the itching is severe.

Peeling

Consult a doctor if peeling is a concern.

Photosensitivity

To manage photosensitivity, apply sunscreen to the skin regularly. Avoid prolonged sun exposure.

Comparison between studies

Similarities

Both studies assessed the efficacy and safety of tretinoin topical.

Differences

2 focused on treating solar lentigines, while 1 focused on treating acne vulgaris.

Practical implications

Tretinoin topical can cause a variety of side effects on the skin. It's crucial to use tretinoin topical correctly as directed by a doctor. It's important to note that pregnant or breastfeeding women should not use tretinoin topical.

Limitations of current research

There is still a need for further research on tretinoin topical. Long-term side effects and safety require further study.

Future research directions

Further research is needed to assess the long-term side effects and safety of tretinoin topical. Research is also needed to develop methods for reducing side effects from tretinoin topical.

Conclusion

Tretinoin topical is an effective medication for treating various skin conditions such as solar lentigines and acne vulgaris. However, tretinoin topical can cause a variety of side effects on the skin. It's crucial to use tretinoin topical correctly as directed by a doctor. It's important to note that pregnant or breastfeeding women should not use tretinoin topical. Further research is needed to address the long-term effects and safety of tretinoin topical.

Literature analysis of 2 papers
Positive Content
1
Neutral Content
0
Negative Content
1
Article Type
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1
2
1.

Concomitant administration of vitamin E does not change the side effects of isotretinoin as used in acne vulgaris: a randomized trial.

Author: StraussJ S, GottliebA B, JonesT, KooJ Y, LeydenJ J, LuckyA, PappasA A, McLaneJ, LeachE E

No improvement in retinoid side effects

Vitamin E did not significantly ameliorate retinoid side effects when combined with isotretinoin in the treatment of acne.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

2.

Treatment of solar lentigines.

Author: OrtonneJean-Paul, PandyaAmit G, LuiHarvey, HexselDoris

Treatment of solar lentigines
Side effects

Cryotherapy is considered first-line therapy for solar lentigines. Lasers are also an effective treatment option. Topical therapy, including fixed double combinations and retinoids, can be used as an alternative or as maintenance therapy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

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