著者: SeiwertTanguy Y, KochannySara, WoodKevin, WordenFrancis P, AdkinsDouglas, WadeJames L, SleckmanBethany G, AndersonDaniel, BrissonRyan J, KarrisonTheodore, StadlerWalter M, VokesEverett E

原題: A randomized phase 2 study of temsirolimus and cetuximab versus temsirolimus alone in recurrent/metastatic, cetuximab-resistant head and neck cancer: The MAESTRO study.

著者: ZhangXiaoli, ChenWei, GaoQiong, YangJunsheng, YanXueni, ZhaoHan, SuLin, YangMeimei, GaoChenlang, YaoYao, InokiKen, LiDan, ShaoRong, WangShiyi, SahooNirakar, KudoFumitaka, EguchiTadashi, RuanBenfang, XuHaoxing

原題: Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.

著者: BellmuntJ, SzczylikC, FeingoldJ, StrahsA, BerkenblitA

原題: Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features.

著者: AlamMd Maksudul, Marin FerminJanmaris, SpillerPatrick T, BurnettChaning, RongXiaohua, Moore-MedlinTara, MaxwellCaden O, KhandelwalAlok R, NathanCherie-Ann O

原題: Rapalogs induce non-apoptotic, autophagy-dependent cell death in HPV-negative TP53 mutant head and neck squamous cell carcinoma.

著者: WangDenise, EisenHoward J

原題: Mechanistic Target of Rapamycin (mTOR) Inhibitors.

著者: PirosaMaria C, ZhangLu, HitzFelicitas, NovakUrban, HessDagmar, TerrotTatiana, PascaleMariarosa, MazzucchelliLuca, BertoniFrancesco, CavalliFranco, ZuccaEmanuele, StathisAnastasios

原題: A phase I trial of inotuzumab ozogamicin in combination with temsirolimus in patients with relapsed or refractory CD22-positive B-cell non-Hodgkin lymphomas.

著者: LiHua-Wen, LiuMu-Biao, JiangXue, SongTing, FengShu-Xian, WuJing-Ya, DengPeng-Fei, WangXiao-Yu

原題: GALNT14 regulates ferroptosis and apoptosis of ovarian cancer through the EGFR/mTOR pathway.

著者: MascarenhasLeo, ChiYueh-Yun, HingoraniPooja, AndersonJames R, LydenElizabeth R, RodebergDavid A, IndelicatoDaniel J, KaoSimon C, DasguptaRoshni, SpuntSheri L, MeyerWilliam H, HawkinsDouglas S

原題: Randomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children's Oncology Group.

著者: ShiGuoli, ChiramelAbhilash I, LiTiansheng, LaiKin Kui, KenneyAdam D, ZaniAshley, EddyAdrian, MajdoulSaliha, ZhangLizhi, DempseyTirhas, BearePaul A, KarSwagata, YewdellJonathan W, BestSonja M, YountJacob S, ComptonAlex A

原題: Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2.

著者: FahimAmmad, RehmanZaira, BhattiMuhammad Faraz, VirkNasar, AliAmjad, RashidAmir, ParachaRehan Zafar

原題: The Route to 'Chemobrain' - Computational probing of neuronal LTP pathway.

著者: AlammarHajar, NassaniRayan, AlshehriMana M, AljohaniAlaa A, AlrfaeiBahauddeen M

原題: Deficiency in the Treatment Description of mTOR Inhibitor Resistance in Medulloblastoma, a Systematic Review.

著者: HeJichao, McLaughlinRonan P, van der NoordVera, FoekensJohn A, MartensJohn W M, van WestenGerard, ZhangYinghui, van de WaterBob

原題: Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer.

著者: KobayashiYukari, YamadaDaisuke, KawaiTaketo, SatoYusuke, TeshimaTaro, YamadaYuta, NakamuraMasaaki, SuzukiMotofumi, MatsumotoAkihiko, NakagawaTohru, HosoiAkihiro, NagaokaKoji, KarasakiTakahiro, MatsushitaHirokazu, KumeHaruki, KakimiKazuhiro

原題: Different immunological effects of the molecular targeted agents sunitinib, everolimus and temsirolimus in patients with renal cell carcinoma.

著者: FarleyJohn H, BradyWilliam E, O'MalleyDavid, FujiwaraKeiichi, YonemoriKan, BonebrakeAlbert, SecordAngeles Alvarez, StephanJean-Marie, WalkerJoan L, NamJoo-Hyun, BirrerMichael J, GershensonDavid M

原題: A phase II evaluation of temsirolimus with carboplatin and paclitaxel followed by temsirolimus consolidation in clear cell ovarian cancer: An NRG oncology trial.

著者: YamaguchiShion, MurayamaRumi, SatohEisaku, InoueTadao, IseYuya

原題: Effects of Tyrosine Kinase Inhibitors on Blood Pressure in Patients with Unresectable or Advanced Recurrent Renal Cell Carcinoma-Bayes-Mixed Treatment Comparison Meta-Analysis.

著者: ParkHaeseong, WilliamsKerry, TrikalinosNikolaos A, LarsonSarah, TanBenjamin, WaqarSaiama, SureshRama, MorgenszternDaniel, Van TineBrian A, GovindanRamaswamy, LuoJingqin, LockhartA Craig, Wang-GillamAndrea

原題: A phase I trial of temsirolimus and erlotinib in patients with refractory solid tumors.

著者: KaraNirit Z, Flaisher-GrinbergShlomit, AndersonGrant W, AgamGalila, EinatHaim

原題: Mood-stabilizing effects of rapamycin and its analog temsirolimus: relevance to autophagy.

著者: PalSumanta, GongJun, MhatreShivani K, LinShih-Wen, SurinachAndy, OgaleSarika, VohraRini, WallenHerschel, GeorgeDaniel

原題: Real-world treatment patterns and adverse events in metastatic renal cell carcinoma from a large US claims database.

著者: IvanovaElena, KuraguchiMari, XuMan, PortellAndrew J, TausLuke, DialaIrmina, LalaniAlshad S, ChoiJihyun, ChambersEmily S, LiShuai, LiuShengwu, ChenTing, BarbieThanh U, OxnardGeoffrey R, HaworthJacob J, WongKwok-Kin, DahlbergSuzanne E, ArefAmir A, BarbieDavid A, BahcallMagda, PaweletzCloud P, JännePasi A

原題: Use of <i>Ex</i> <i>Vivo</i> Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for <i>HER2</i> Mutant Non-Small Cell Lung Cancer.

著者: BlázquezCristina, Ruiz-CalvoAndrea, Bajo-GrañerasRaquel, BaufretonJérôme M, ReselEva, VarilhMarjorie, Pagano ZottolaAntonio C, MarianiYamuna, CannichAstrid, Rodríguez-NavarroJosé A, MarsicanoGiovanni, Galve-RoperhIsmael, BellocchioLuigi, GuzmánManuel

原題: Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination.

著者: LinHong, SalechFelipe, LimAnthony, VogrinSara, DuqueGustavo

原題: The effect of rapamycin and its analogues on age-related musculoskeletal diseases: a systematic review.

著者: KimSeo Yun, JeongEun-Hui, LeeTae-Gul, KimHye-Ryoun, KimCheol Hyeon

原題: The Combination of Trametinib, a MEK Inhibitor, and Temsirolimus, an mTOR Inhibitor, Radiosensitizes Lung Cancer Cells.