著者:

原題: Verteporfin: new indication. New indication in complications of high myopia: no sustained benefit.

著者: KatsChantal Jar, JochemsAnouk, JeurissenFrank Jf, LedeboerAletta, van den BergRoland B

原題: Two patients with fluoropyrimidine overdose successfully managed without uridine triacetate.

著者: SeltzerJustin A, FriedmanNathan A, HardinJeremy, GalustHenrik, CantrellF Lee, MinnsAlicia

原題: Oral Capecitabine Exposures and Use of Uridine Triacetate: A 20-Year Retrospective Analysis.

著者: JacobAasems, Sekkath VeeduJaneesh, SeleneInsija, RajRishi, KannanLakshmi, PatelReema

原題: Case report: Uridine triacetate in the management of delayed onset 5-fluorouracil toxicity: A case report and review of literature.

著者: LiYongchang, WuXiaomei, ZhongWei, TangXiangqi

原題: Reversible Toxic Encephalopathy Involving the Cerebellum and Subcortical White Matter Attributed to Capecitabine.

著者: LampropoulouDimitra Ioanna, LaschosKonstantinos, AmylidiAnna-Lea, AngelakiAriadni, SouposNikolaos, BoumpoucheropoulosSotirios, PapadopoulouEirini, NanouEvgenia, ZidianakisVasilios, NasioulasGeorge, FildissisGeorge, AravantinosGerasimos

原題: Fluoropyrimidine-induced toxicity and DPD deficiency.. A case report of early onset, lethal capecitabine-induced toxicity and mini review of the literature. Uridine triacetate: Efficacy and safety as an antidote. Is it accessible outside USA?

著者: SaifMuhammad W

原題: Capecitabine-induced cerebellar toxicity and TYMS pharmacogenetics.

著者: BaldeoCandice, VishnuPrakash, ModyKabir, KasiPashtoon Murtaza

原題: Uridine triacetate for severe 5-fluorouracil toxicity in a patient with thymidylate synthase gene variation: Potential pharmacogenomic implications.

著者: DepetrisIlaria, MarinoDonatella, BonzanoAlessandro, CagnazzoCeleste, FilippiRoberto, AgliettaMassimo, LeoneFrancesco

原題: Fluoropyrimidine-induced cardiotoxicity.

著者: ZuraykMira, KeungYi-Kong, YuDavid, HuEddie Hl

原題: Successful use of uridine triacetate (Vistogard) three weeks after capecitabine in a patient with homozygous dihydropyrimidine dehydrogenase mutation: A case report and review of the literature.

著者: OliverWesley D, DuffyAlison P, HausnerPetr F

原題: Case report of capecitabine toxicity and use of uridine triacetate.

著者: VaudoChristine E, GilBrigitte, GaluskiKari, ZarwanCorrine, NugentFrancis W

原題: Early-Onset 5-Fluorouracil Toxicity in a Patient Negative for Dihydropyrimidine Dehydrogenase Mutations: The Clinical Course of Reversal with Uridine Triacetate.

著者: MaWen Wee, SaifMuhammad Wasif, El-RayesBassel F, FakihMarwan G, CartwrightThomas H, PoseyJames A, KingThomas R, von BorstelReid W, BamatMichael K

原題: Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity.

著者: IsonGwynn, BeaverJulia A, McGuinnW David, PalmbyTodd R, DininJeannette, CharlabRosane, MaratheAnshu, JinRunyan, LiuQi, ChenXiao Hong, YsernXavier, StephensOlen, BaiGe, WangYaning, DorffSarah E, ChengJoyce, TangShenghui, SridharaRajeshwari, PierceWilliam, McKeeAmy E, IbrahimAmna, KimGeoffrey, PazdurRichard

原題: FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs.

著者: SaifMuhammad Wasif, DiasioRobert B

原題: Benefit of uridine triacetate (Vistogard) in rescuing severe 5-fluorouracil toxicity in patients with dihydropyrimidine dehydrogenase (DPYD) deficiency.

著者: SaydoffJoel A, OlariuAna, ShengJin, HuZhongyi, LiQin, GarciaRolando, PeiJiong, SunGrace Y, von BorstelReid

原題: Uridine prodrug improves memory in Tg2576 and TAPP mice and reduces pathological factors associated with Alzheimer's disease in related models.

著者: McEvillyMargaret, PopelasCarl, TremmelBob

原題: Use of uridine triacetate for the management of fluorouracil overdose.

著者: WeinbergMelissa E, RomanMark C, JacobPeyton, WenMichael, CheungPolly, WalkerUlrich A, MulliganKathleen, SchambelanMorris

原題: Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement.

著者: JensenJ Eric, DanielsMelissa, HawsCharlotte, BoloNicolas R, LyooIn Kyoon, YoonSujung J, CohenBruce M, StollAndrew L, RuscheJames R, RenshawPerry F

原題: Triacetyluridine (TAU) decreases depressive symptoms and increases brain pH in bipolar patients.

著者: SaydoffJoel A, GarciaRolando A G, BrowneSusan E, LiuLiansheng, ShengJin, BrennemanDenise, HuZhongyi, CardinSylvain, GonzalezAlexis, von BorstelReid W, GregorioJason, BurrHolly, BealM Flint

原題: Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease.

著者: DoroshowJames H, McCoySheryl, MacdonaldJohn S, IssellBrian F, PatelTaral, CobbPatrick W, YostKathleen J, AbbruzzeseJames L

原題: Phase II trial of PN401, 5-FU, and leucovorin in unresectable or metastatic adenocarcinoma of the stomach: a Southwest Oncology Group study.

著者: GarciaRolando A G, LiuLiansheng, HuZhongyi, GonzalezAlexis, von BorstelReid W, SaydoffJoel A

原題: Severe cytochrome c oxidase inhibition in vivo does not induce a pyrimidine deficiency; neuroprotective action of oral uridine prodrug PN401 requires supraphysiological levels of uridine.

著者: SaifMuhammad Wasif, von BorstelReid

原題: 5-Fluorouracil dose escalation enabled with PN401 (triacetyluridine): toxicity reduction and increased antitumor activity in mice.

著者: KlivenyiPeter, GardianGabrielle, CalingasanNoel Y, YangLichuan, von BorstelReid, SaydoffJoel, BrowneSusan E, BealM Flint

原題: Neuroprotective effects of oral administration of triacetyluridine against MPTP neurotoxicity.

著者: SaydoffJoel A, LiuLian Sheng, GarciaRolando A G, HuZhongyi, LiDonna, von BorstelReid W

原題: Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease.