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The response to inhaled and oral steroids in patients with stable chronic obstructive pulmonary disease.

Author: MagadleR, RabnerM, WaizmanJ, WeinerM, WeinerP, ZamirD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

While some people with COPD respond well to corticosteroid treatment, a significant number do not. The potential benefits of corticosteroids may be outweighed by their side effects. Long-term use of inhaled steroids is generally safe, however, the effectiveness of inhaled corticosteroids for COPD remains unclear, with conflicting findings from studies.
Paper Details　
Original Abstract of the Article :
A significant minority of patients with COPD have favourable response to corticosteroid treatment. In addition, the benefit of corticosteroid treatment may be outweighed by the side-effects. Long-term administration of inhaled steroids is a safe means of treatment. However, only a few studies have a...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2796.1999.00412.x

データ提供：米国国立医学図書館（NLM）

Corticosteroids and Chronic Obstructive Pulmonary Disease (COPD): A Complex Relationship

This study investigates the role of corticosteroids in managing stable COPD, a chronic lung disease that can significantly impact quality of life. It explores the effectiveness of both inhaled and oral corticosteroids in patients with COPD, examining their potential benefits and risks.

Limited Evidence, Mixed Results

The study found that while corticosteroids can be beneficial for some patients with COPD, the response is variable and the risks need to be carefully weighed. The authors highlighted that long-term administration of inhaled corticosteroids is generally safe, but more research is needed to understand their optimal role in treating COPD. Furthermore, they noted that the conflicting results from previous studies necessitate further investigation.

Individualized Treatment Approaches

This study underscores the importance of tailoring treatment approaches for patients with COPD, considering individual factors and response to medication. It highlights the need for a personalized approach to managing COPD, balancing potential benefits with risks. Careful monitoring and regular assessments are crucial for ensuring optimal outcomes.

Dr.Camel's Conclusion

This study is like a desert mirage—it offers a glimpse of potential benefits of corticosteroids in COPD but reminds us that these benefits are not always clear or straightforward. The study emphasizes the need for careful consideration of individual patient needs and ongoing research to develop effective and safe treatment strategies for this complex disease.
Date :
  1. Date Completed 1999-04-07
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

10095821

DOI: Digital Object Identifier

10.1046/j.1365-2796.1999.00412.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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