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Suppression of airway inflammation by theophylline in adult bronchial asthma.

Author: DoiM, HiroseM, HoriguchiT, ImazuM, KasaharaJ, MiyazakiJ, SasakiY, ShigaM, TachikawaS

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study discusses the role of chronic continuous airway inflammation caused by eosinophils in the pathophysiology of bronchial asthma. The study notes that theophylline, a conventionally used bronchodilator, may have anti-inflammatory effects.
Paper Details　
Original Abstract of the Article :
Chronic continuous airway inflammation caused by eosinophils has been noted to play critical roles in the pathophysiology of bronchial asthma, in addition to reversible obstruction and hypersensitivity of the respiratory tract. Therefore, suppression of chronic airway inflammation has become more im...See full text at original site
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引用元：
https://doi.org/10.1159/000029353

データ提供：米国国立医学図書館（NLM）

Theophylline and Airway Inflammation: A Double-Edged Sword in Asthma Treatment

This research investigates the potential of theophylline, a commonly used bronchodilator, to suppress airway inflammation in patients with adult bronchial asthma. The authors provide an overview of the role of airway inflammation in asthma pathogenesis and discuss the evidence for theophylline's anti-inflammatory effects. The study highlights theophylline's potential as a multi-faceted treatment option for asthma, addressing both bronchospasm and airway inflammation.

A Dual Role for Theophylline: Bronchodilation and Anti-Inflammation

The study underscores the potential of theophylline to exert both bronchodilator and anti-inflammatory effects, providing a multi-faceted approach to managing asthma. This finding is particularly significant given the growing recognition of the importance of addressing chronic airway inflammation in asthma treatment. Theophylline's ability to target both symptoms and underlying inflammation offers a promising avenue for improving asthma control and patient outcomes.

Navigating the Desert of Asthma: Theophylline's Potential

This research provides valuable insights into the potential of theophylline as a treatment option for asthma. It highlights the drug's ability to address both bronchospasm and airway inflammation, offering a multi-pronged approach to managing this complex condition. The study encourages further investigation into the role of theophylline in asthma management, exploring its potential to improve patient outcomes and enhance quality of life for those living with this chronic condition.

Dr. Camel's Conclusion

This study provides compelling evidence for the potential of theophylline to address both bronchospasm and airway inflammation in asthma, offering a more holistic approach to managing this complex condition. The research underscores the importance of exploring the full spectrum of therapeutic effects of commonly used medications, potentially leading to more effective treatment strategies and better outcomes for patients. It's like discovering a hidden oasis in the desert of asthma, providing a refreshing and rejuvenating source of relief.

Date :
  1. Date Completed 1999-06-17
  2. Date Revised 2017-11-01
Further Info :

Pubmed ID

10202315

DOI: Digital Object Identifier

10.1159/000029353

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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