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Chemotherapy alternated with radiotherapy in the treatment of advanced head and neck carcinoma: predictive factors of outcome.

Author: BacigalupoA, BenassoM, CorvòR, NumicoG, RossoR, SanguinetiG, SormaniM P, VitaleV

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study examined 115 patients with advanced head and neck cancer (stages III and IV) who received alternating chemoradiotherapy. The study focused on how factors before treatment and during treatment influenced local-regional control (cancer not spreading in the treated area) and overall survival. Patients included in the analysis had a good performance status (PS ≤ 1) and received radiotherapy doses within a 5% range of what was planned.
Paper Details　
Original Abstract of the Article :
To investigate the impact of pretreatment and treatment-related factors on local-regional control and overall survival rates in advanced (III and IV stage) head and neck cancer patients treated with alternating chemoradiotherapy, a selected group of 115 patients who had PS < or = 1 and received a to...See full text at original site
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引用元：
https://doi.org/10.1016/s0360-3016(98)00546-x

データ提供：米国国立医学図書館（NLM）

Chemotherapy and Radiotherapy: A Powerful Combination for Advanced Head and Neck Cancer

Head and neck cancer is a complex and challenging disease, and this research investigates the effectiveness of alternating chemoradiotherapy in treating advanced stages of the disease. The study uses a retrospective analysis of a large cohort of patients, examining factors that predict treatment outcomes.

Alternating Chemoradiotherapy: A Promising Treatment Approach

The research suggests that alternating chemoradiotherapy, a treatment strategy that combines chemotherapy and radiotherapy, is a promising approach for treating advanced head and neck cancer. Think of it like a well-coordinated caravan, where chemotherapy and radiotherapy work together to combat the disease.

Personalized Treatment Strategies: A Key to Success

This research highlights the importance of personalized treatment strategies in head and neck cancer, taking into account individual patient characteristics and factors that may influence treatment outcomes. Just as a camel needs to adjust its journey based on the terrain, treatment plans should be tailored to the specific needs of each patient.

Dr.Camel's Conclusion

The desert of head and neck cancer can be a daunting landscape, but this research offers a beacon of hope, suggesting that alternating chemoradiotherapy can be a powerful weapon in the fight against this challenging disease. By understanding the individual needs of each patient and tailoring treatment plans accordingly, we can create a more personalized and effective approach to care, offering hope for a brighter future for those facing this difficult journey.

Date :
  1. Date Completed 1999-05-06
  2. Date Revised 2019-07-08
Further Info :

Pubmed ID

10219807

DOI: Digital Object Identifier

10.1016/s0360-3016(98)00546-x

Related Literature

Article Analysis
・Effective treatment of head and neck cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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