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Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: a randomized controlled trial.

Author: BrownG A, KingD S, ParsonsK A, ReifenrathT A, SharpR L, UhlN L, VukovichM D

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Androstenedione supplementation does not increase serum testosterone concentrations or enhance skeletal muscle adaptations to resistance training in normotestosterogenic young men. It may result in adverse health consequences.
Paper Details　
Original Abstract of the Article :
CONTEXT: Androstenedione, a precursor to testosterone, is marketed to increase blood testosterone concentrations as a natural alternative to anabolic steroid use. However, whether androstenedione actually increases blood testosterone levels or produces anabolic androgenic effects is not known. OBJE...See full text at original site
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引用元：
https://doi.org/10.1001/jama.281.21.2020

データ提供：米国国立医学図書館（NLM）

Androstenedione's Impact on Testosterone and Muscle Growth

This study investigates the effects of androstenedione, a naturally occurring hormone, on testosterone levels and muscle growth in young men. It's like studying the impact of a sandstorm on a desert ecosystem - we need to understand how this change affects the balance and growth of the environment! This study looked at the effects of androstenedione supplementation on men participating in resistance training. The results showed that androstenedione did not significantly increase testosterone levels or enhance muscle growth.

Androstenedione's Lack of Effect on Testosterone and Muscle Growth

This study found that androstenedione supplementation did not significantly increase testosterone levels or enhance muscle growth in young men participating in resistance training. This suggests that androstenedione, despite its marketing as a natural testosterone booster, does not provide the expected benefits for muscle building. It's like discovering that the desert oasis you hoped would bring growth and prosperity is actually a mirage, leading you to reconsider your expectations.

Understanding the Impact of Supplements on Health

This research underscores the importance of understanding the potential risks and benefits of supplements. It is crucial to be informed about the scientific evidence and to consult with a healthcare professional before taking any supplements, especially those marketed for enhancing performance or boosting testosterone levels. It's like navigating a desert – carefully considering each path and seeking guidance from experienced travelers.

Dr. Camel's Conclusion

This study provides valuable insights into the impact of androstenedione on testosterone levels and muscle growth. While it may not be the magic bullet for enhancing muscle growth, it highlights the importance of critically evaluating supplements and consulting with a healthcare professional before making decisions about your health. It's like navigating the desert – always being prepared, seeking guidance, and making informed decisions based on the available information.

Date :
  1. Date Completed 1999-06-15
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

10359391

DOI: Digital Object Identifier

10.1001/jama.281.21.2020

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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