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[Interferon therapy of chronic viral hepatitis in Hungary: 5-year experience. A multicenter study].

Author: GóglA, MüllerE, PárA, TelegdyL

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study reports on the treatment of chronic viral hepatitis with interferon (IFN) in Hungary. Over 1,000 patients with chronic hepatitis B or C were included in the study. The results showed that IFN therapy achieved varying rates of seroconversion and sustained remission, with the highest remission rate seen with a combination of IFN and ribavirin.
Paper Details　
Original Abstract of the Article :
In Hungary over the past 5 years more than thousand patients with chronic viral hepatitis have been examined and included in a treatment program with interferon (IFN) at 16 major hepatology centers, using unified diagnostic and therapeutical criteria. Authors give an account of their experiences on ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/10377733

データ提供：米国国立医学図書館（NLM）

Interferon Therapy for Chronic Viral Hepatitis: A Five-Year Journey

This study takes us on a five-year journey through the world of chronic viral hepatitis, examining the use of interferon (IFN) therapy in Hungary. The authors describe the clinical features of patients with chronic viral hepatitis and analyze the results of IFN treatment, aiming to provide insights into the efficacy and limitations of this therapy.

Navigating the Landscape of Treatment: A Multifaceted Approach

The study found that IFN therapy had varying degrees of success in treating chronic viral hepatitis, with a sustained remission rate of 33% for hepatitis B virus (HBV) infection and 36% for chronic hepatitis C. Interestingly, the researchers observed that factors such as fibrosis and baseline HCV-RNA level were predictors of response to treatment. This highlights the importance of individualized treatment strategies, considering the unique characteristics of each patient and their specific viral infection.

Seeking New Horizons: The Quest for Effective Therapies

This study underscores the ongoing need for novel and effective treatments for chronic viral hepatitis. While IFN therapy has shown some success, the study's findings highlight the need for more research and development of alternative therapies. It's like exploring a vast and uncharted desert – while IFN therapy has provided a map, the search for more effective treatments continues, seeking new oases of hope in the vast expanse of viral diseases.

Dr.Camel's Conclusion

Chronic viral hepatitis is a challenging condition, like a seemingly endless desert of symptoms and potential complications. While IFN therapy has shown some promise, it’s not a magic bullet. The research underscores the need for continued exploration and innovation in this field, seeking new pathways to a healthier future.

Date :
  1. Date Completed 1999-07-08
  2. Date Revised 2009-10-21
Further Info :

Pubmed ID

10377733

DOI: Digital Object Identifier

10377733

SNS
PICO Info
in preparation
Languages

Hungarian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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