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Effect of parenteral antibiotic administration on persistence of vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract.
Author: DonskeyC J, HanrahanJ A, HuttonR A, RiceL B
Original Abstract of the Article :
A mouse model of vancomycin-resistant Enterococcus faecium (VRE) intestinal colonization was used to study the effect of different subcutaneous antibiotics on persistence and density of VRE colonization. Gastric inoculation of a clinical VanB VRE isolate, in conjunction with oral vancomycin in drink...See full text at original site
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引用元:
https://doi.org/10.1086/314874
データ提供:米国国立医学図書館(NLM)
The Persistence of Vancomycin-Resistant Enterococcus faecium (VRE) in the Gut: A Mouse Model Study
In the realm of infectious diseases, the rise of antibiotic resistance poses a significant challenge. This study delves into the complex world of vancomycin-resistant Enterococcus faecium (VRE), investigating the impact of different antibiotics on its persistence in the gut. Using a mouse model, the researchers meticulously analyzed the effects of various antibiotics on VRE colonization. Their findings, much like a camel navigating a treacherous desert landscape, shed light on the influence of antibiotic selection on the persistence of VRE in the gut. This research underscores the importance of carefully considering antibiotic choices to minimize the development of antibiotic resistance.
Antibiotics and the Gut: A Complex Relationship
The study reveals that vancomycin and antibiotics with potent antianaerobic activity can promote persistent VRE colonization in the gut. This is a crucial finding as it highlights the need to choose antibiotics with care, considering their potential impact on gut microbiota and the risk of promoting antibiotic resistance. The study's results are like a warning sign in the desert, reminding us to be cautious in our use of antibiotics.
A Healthy Gut: Strategies for Minimizing Antibiotic Resistance
The study underscores the importance of judicious antibiotic use to minimize the development of antibiotic resistance. This includes only using antibiotics when necessary, completing the full course of treatment as prescribed, and avoiding unnecessary antibiotic exposure. Similar to a camel adapting to the desert environment, we can take steps to protect the delicate balance of our gut microbiota and minimize the risk of antibiotic resistance.
Dr.Camel's Conclusion
This study underscores the importance of careful antibiotic selection in the context of VRE infections. It's like choosing the right path in the desert to avoid getting lost or stranded. The research provides valuable insights into the complex relationship between antibiotics, gut microbiota, and antibiotic resistance. It serves as a reminder to approach antibiotic use with caution and to explore alternative strategies for managing infections whenever possible.
Date :
- Date Completed 1999-09-07
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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