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Tramadol suppositories are less suitable for post-operative pain relief than rectal acetaminophen/codeine.

Author: PluimM A, RuprehtJ, VultoA G, WegenerJ T

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Tramadol suppositories were less effective than acetaminophen/codeine suppositories for post-operative pain due to a significantly higher incidence of nausea and vomiting (84% vs. 31%).
Paper Details　
Original Abstract of the Article :
The suitability of tramadol suppositories for inclusion in our hospital formulary for the treatment of mild to moderate post-operative pain was evaluated. In an open randomized trial, rectal tramadol was compared with our standard treatment acetaminophen/codeine suppositories. We expected tramadol t...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2346.1999.00520.x

データ提供：米国国立医学図書館（NLM）

Tramadol vs. Acetaminophen/Codeine: Navigating Post-Operative Pain Relief

In the vast and often-unpredictable landscape of post-operative pain management, finding effective and safe solutions is a constant challenge. This study, like a seasoned camel seeking the best oasis, explores the efficacy of tramadol suppositories compared to the standard treatment of acetaminophen/codeine suppositories. The research, conducted as an open randomized trial, aimed to determine whether tramadol offered comparable pain relief with fewer side effects. The study found that, while both treatments provided similar levels of pain relief, tramadol was associated with a significantly higher incidence of nausea and vomiting. This finding highlights the importance of carefully considering the individual patient's needs and potential side effects when choosing a pain management strategy.

Navigating the Side Effects of Tramadol

The study found that tramadol suppositories were associated with a significantly higher incidence of nausea and vomiting compared to acetaminophen/codeine suppositories (84% vs 31%). This difference was statistically significant, with a relative risk of 2.7 for experiencing nausea while on tramadol. These findings suggest that, while tramadol may be effective for some patients, its potential side effects should be carefully considered.

Balancing Pain Relief and Side Effects: A Desert Oasis of Choices

Post-operative pain management is like a desert journey—a delicate balancing act between finding relief while navigating potential side effects. This study reveals that tramadol, while effective for some, carries a higher risk of nausea and vomiting. This knowledge empowers patients to engage in informed discussions with their healthcare providers, weighing the benefits and potential drawbacks of different pain management options.

Dr. Camel's Conclusion

This study offers valuable insights into the complex landscape of post-operative pain management, reminding us that the journey to relief can be complex and require thoughtful consideration of potential side effects. When choosing pain medications, the unique needs and preferences of each patient should be carefully considered, just as a wise camel chooses the best path through a desert.

Date :
  1. Date Completed 1999-09-30
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

10457880

DOI: Digital Object Identifier

10.1046/j.1365-2346.1999.00520.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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