Therapeutic considerations of L-glutamine: a review of the literature.

Author: MillerA L

Paper Details 
Original Abstract of the Article :
The most abundant amino acid in the bloodstream, L-glutamine fulfills a number of biochemical needs. It operates as a nitrogen shuttle, taking up excess ammonia and forming urea. It can contribute to the production of other amino acids, glucose, nucleotides, protein, and glutathione. Glutamine is pr...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/10468648

データ提供:米国国立医学図書館(NLM)

The Importance of L-Glutamine: A Vital Amino Acid

In the vast desert of our bodies, L-glutamine stands as an oasis, a vital nutrient that plays a crucial role in various biochemical processes. This research delves into the therapeutic significance of this abundant amino acid, examining its role in maintaining cellular health and its potential benefits in various medical conditions. The study utilized a comprehensive review of existing literature to understand the diverse functions of L-glutamine and its implications for human health.

The researchers uncovered the remarkable ability of L-glutamine to act as a nitrogen shuttle, effectively transporting excess ammonia and converting it into urea, a process essential for maintaining the delicate equilibrium of our internal environment. Furthermore, L-glutamine serves as a building block for other amino acids, glucose, nucleotides, protein, and glutathione, all of which are fundamental components of our biological machinery. This research highlights the diverse roles of L-glutamine, providing valuable insights into its importance in maintaining optimal cellular function.

The Significance of L-Glutamine in Medical Treatment

This study emphasizes the critical role of L-glutamine in various medical contexts. For instance, it underscores the importance of L-glutamine supplementation in the treatment of trauma and surgical patients. The study provides compelling evidence that supplementing with L-glutamine can decrease the incidence of infection in these patients. This finding is particularly relevant in the context of post-operative recovery, where maintaining immune function is crucial for preventing complications.

L-Glutamine and Cancer Treatment: A Balancing Act

The researchers also explore the complex relationship between L-glutamine and cancer treatment. While L-glutamine can help offset muscle depletion caused by cancer, it also has the potential to stimulate the growth of certain tumors. This delicate balance underscores the need for careful consideration when using L-glutamine in conjunction with cancer chemotherapy and radiotherapy. However, the study sheds light on the potential benefits of L-glutamine in mitigating the gastrointestinal and oral side effects associated with cancer treatment, potentially enhancing the effectiveness of chemotherapy drugs.

Dr. Camel's Conclusion

In the vast desert of our bodies, L-glutamine emerges as a vital nutrient with a multifaceted role in maintaining cellular health and supporting various medical treatments. While L-glutamine holds significant promise, further research is needed to fully understand its complex interplay with cancer and to develop safe and effective strategies for its use in different medical contexts. As a researcher, I find this study's exploration of L-glutamine's diverse roles particularly intriguing. It serves as a reminder that even in the seemingly simple world of amino acids, there are still many hidden secrets to uncover.

Date :
  1. Date Completed 1999-10-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

10468648

DOI: Digital Object Identifier

10468648

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.