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Conventional and extended-release etodolac for postsurgical dental pain.

Author: AppelA, CooperS A, GallegosL T, HershE V, LevinL M, McGoldrickK, ReynoldsD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Extended-release etodolac 1200 mg was found to be effective in relieving postoperative pain following third molar surgery and had a prolonged analgesic duration of 12-24 hours.
Paper Details　
Original Abstract of the Article :
This double-masked, parallel-group, randomized study compared the analgesic efficacy and tolerability of a single investigational 1200-mg dose of extended-release etodolac with those of a single 400-mg dose of extended-release etodolac and twice-daily doses of conventional etodolac 200 and 400 mg an...See full text at original site
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引用元：
https://doi.org/10.1016/s0149-2918(99)80034-4

データ提供：米国国立医学図書館（NLM）

Comparing Etodolac Formulations for Postsurgical Dental Pain

This research explores the realm of [postsurgical dental pain], a common and often debilitating experience. The researchers, like skilled pharmacists seeking the most effective pain relief, compared the efficacy and safety of different formulations of [etodolac] in managing [postsurgical pain] after [surgical removal of impacted third molars]. Their findings offer valuable insights into the optimal approach to managing this type of pain.

The Efficacy and Safety of Different Etodolac Formulations

The study, like a meticulously controlled experiment in a dental research lab, found that both [conventional] and [extended-release etodolac] were significantly more effective than [placebo] in reducing [postsurgical dental pain]. The researchers found that [extended-release etodolac 1200 mg] had a [longer duration of action] than [conventional etodolac], offering [prolonged pain relief]. Importantly, [no serious adverse events] were observed in the study, indicating a favorable safety profile for both formulations.

Choosing the Right Pain Relief Option for Postsurgical Dental Pain

This study provides valuable guidance for choosing the most appropriate pain relief option for [postsurgical dental pain]. The researchers' findings suggest that [extended-release etodolac 1200 mg] may be particularly beneficial for individuals seeking [prolonged pain relief]. Just as a camel seeks out a source of water to quench its thirst, patients undergoing dental surgery may find relief and comfort through the use of effective pain medication.

Dr. Camel's Conclusion

This research offers a comprehensive analysis of the efficacy and safety of different [etodolac] formulations in managing [postsurgical dental pain]. The findings highlight the potential benefits of [extended-release etodolac] for providing prolonged pain relief. Just as a camel relies on its strength and endurance to navigate the desert, individuals undergoing dental surgery may find comfort and healing through the use of effective pain management strategies.

Date :
  1. Date Completed 1999-11-04
  2. Date Revised 2019-09-21
Further Info :

Pubmed ID

10485505

DOI: Digital Object Identifier

10.1016/s0149-2918(99)80034-4

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・Side Effects of etodolac
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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