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Infant vaccinations and risk of childhood acute lymphoblastic leukaemia in the USA.

Author: GridleyG, GrovesF D, LinetM S, NegliaJ P, RobisonL L, ShuX O, WacholderS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study found no relationship between most infant vaccinations and the risk of childhood ALL, except for the conjugate Haemophilus influenzae type b (Hib) vaccine, which may be associated with a reduced risk of ALL.
Paper Details　
Original Abstract of the Article :
Previous studies have suggested that infant vaccinations may reduce the risk of subsequent childhood leukaemia. Vaccination histories were compared in 439 children (ages 0-14) diagnosed with acute lymphoblastic leukaemia (ALL) in nine Midwestern and Mid-Atlantic states (USA) between 1 January 1989 a...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374362/

データ提供：米国国立医学図書館（NLM）

Infant Vaccinations and Childhood Leukemia Risk

The relationship between infant vaccinations and childhood leukemia has been a subject of debate. This study aimed to investigate whether infant vaccinations, particularly the Haemophilus influenzae type b (Hib) vaccine, are associated with an increased or decreased risk of childhood acute lymphoblastic leukemia (ALL). The researchers compared vaccination histories of 439 children diagnosed with ALL and 439 matched controls. They found no association between most infant vaccinations and ALL risk. However, the study suggested that infants receiving the conjugate Hib vaccine may have a reduced risk of developing ALL. Further research is needed to confirm this association and understand the underlying mechanisms.

Potential Protective Role of Hib Vaccine

This study's findings suggest that the conjugate Hib vaccine might offer protection against ALL. While more research is needed to confirm this association, it raises intriguing questions about the potential benefits of vaccination beyond preventing specific diseases.

Dr.Camel's Perspective on Childhood Leukemia and Vaccination

Imagine a desert oasis, a source of life and protection against the harsh environment. Vaccinations are like oases in the vast sea of childhood health, providing protection against various diseases. This study suggests that the Hib vaccine, like a particularly nourishing oasis, might even offer extra protection against leukemia. While further research is needed, this study encourages us to appreciate the multifaceted benefits of vaccination.

Dr.Camel's Conclusion

The relationship between infant vaccinations and childhood leukemia is a complex one, requiring further exploration. This study suggests a potential protective role for the conjugate Hib vaccine, adding another layer to the benefits of vaccination. Like a camel seeking shade in a desert oasis, we must continue our journey of understanding the intricate relationship between vaccinations and childhood health.

Date :
  1. Date Completed 1999-09-30
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

10487630

DOI: Digital Object Identifier

PMC2374362

SNS
PICO Info
in preparation
Languages

English

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