Paper Details 
Original Abstract of the Article :
The effects of gold sodium thiomalate (GST) and auranofin (SK&F D-39162) on cell-mediated immunity were investigated using oxazolone-induced contact sensitivity and delayed hypersensitivity to sheep red blood cells. C57Bl mice were sensitized to oxazolone on day 0 and challenged either 45 or 72 h la...See full text at original site
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引用元:
https://doi.org/10.1007/BF00910733

データ提供:米国国立医学図書館(NLM)

Gold and Immunity: A Journey Through the Desert of Immunology

Imagine a vast desert landscape where the immune system is constantly battling invaders. This study investigates the effects of gold compounds, gold sodium thiomalate (GST) and auranofin (SK&F D-39162), on cell-mediated immunity. The authors used two models of immune responses: contact sensitivity and delayed hypersensitivity to sheep red blood cells, testing the effects of the gold compounds in mice. The study found that both GST and auranofin stimulated immune responses, but auranofin was more effective in stimulating cell-mediated immunity than GST, suggesting a potential for these compounds to modulate immune responses.

Gold Compounds and Immune Modulation: A Double-Edged Sword

The study's findings highlight the potential of gold compounds to modulate immune responses, suggesting a possible role in treating autoimmune diseases. However, it's important to note that these effects were observed in mice and further research is needed to confirm their relevance to human health. The complex interactions between gold compounds and the immune system warrant careful investigation and caution in their application.

Navigating the Desert of Immunology: A Guide to Understanding Immune Function

The immune system is a complex and intricate network of cells and tissues. Understanding the mechanisms underlying immune responses is crucial for developing effective treatments for autoimmune diseases and other immune-related conditions. This research contributes to our understanding of how gold compounds can influence immune function, providing valuable insights for future research and clinical applications.

Dr.Camel's Conclusion

This research delves into the intriguing relationship between gold compounds and the immune system. While gold compounds have shown potential for modulating immune responses, their effects are complex and require further investigation. This research highlights the importance of understanding the delicate balance of the immune system and the need for cautious and personalized approaches when considering gold compounds for therapeutic purposes.

Date :
  1. Date Completed 1979-04-28
  2. Date Revised 2019-09-18
Further Info :

Pubmed ID

104929

DOI: Digital Object Identifier

10.1007/BF00910733

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Languages

English

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