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Immunogenicity and safety of Haemophilus influenzae type b conjugate vaccine (HibTITER) and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER (TETRAMUNE) in two-month-old infants.

Author: ChangP F, ChiuH H, HuangL M, LeeC Y, LeeP I, TsaiS Y

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study was undertaken to evaluate the safety and immunogenicity of a combination vaccine (TETRAMUNE) of conjugate Haemophilus influenzae type b (Hib) vaccine (HibTITER) and DTP (Diphtheria, Tetanus and Pertussis) vaccine. Serologic responses were largely comparable between the two vaccine groups; almost all subjects were seropositive to Hib PRP and were protected against diphtheria and tetanus after 2 doses of vaccine and mounted prominent responses to the components of Bordetella pertussis.
Paper Details　
Original Abstract of the Article :
A study was undertaken to evaluate the safety and immunogenicity of a combination vaccine (TETRAMUNE) of conjugate Haemophilus influenzae type b (Hib) vaccine (HibTITER) and DTP (Diphtheria, Tetanus and Pertussis) vaccine. A total of 93 healthy children were randomized to receive either TETRAMUNE (c...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/10496155

データ提供：米国国立医学図書館（NLM）

A Combined Vaccine Strategy: Safety and Immunogenicity of Haemophilus influenzae type b Conjugate Vaccine

Haemophilus influenzae type b (Hib) infection, like a treacherous desert sandstorm, can cause serious illness in infants. This research investigates the safety and immunogenicity of a combined vaccine containing both Hib conjugate vaccine (HibTITER) and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER (TETRAMUNE). The authors, like skilled vaccine developers, meticulously evaluate the effectiveness and safety of these vaccines in two-month-old infants.

A Combined Approach: Safety and Efficacy of Combined Vaccines

The study demonstrates that HibTITER is highly immunogenic and safe when administered concurrently with DTP vaccine. TETRAMUNE, the combined vaccine, was also found to be safe and immunogenic, potentially reducing the number of injections required to achieve the same level of protection. This combined approach, like a caravan traveling together for mutual protection, offers a more convenient and efficient method for vaccinating infants.

Protecting Our Future: The Importance of Vaccination

This research underscores the importance of vaccination in protecting infants from serious illnesses. Like a protective oasis in a harsh desert, vaccines provide a vital shield against potentially life-threatening diseases. This study provides further evidence for the effectiveness and safety of combined vaccine strategies.

Dr.Camel's Conclusion

This study highlights the importance of combined vaccine strategies in protecting infants from Hib infection and other serious diseases. Like a camel caravan navigating a challenging desert, this research provides a roadmap for healthcare professionals to implement effective and safe vaccination programs, ensuring the health and well-being of future generations.

Date :
  1. Date Completed 1999-10-07
  2. Date Revised 2007-06-21
Further Info :

Pubmed ID

10496155

DOI: Digital Object Identifier

10496155

SNS
PICO Info
in preparation
Languages

English

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