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The gastroduodenal effects of buffered aspirin, carprofen, and etodolac in healthy dogs.
Author: DuncanR B, GimbertK, JohnstonS A, LeibM S, MariniM, ReimerD C, ReimerM E
Original Abstract of the Article :
Twenty-four healthy mixed-breed dogs were divided into 4 groups. Group 1 received a placebo p.o. q12h, group 2 received an average of 16.5 (15.1-17.8) mg/kg buffered aspirin p.o. q12h, group 3 received an average of 2.2 (2.0-2.4) mg/kg carprofen p.o. q12h, and group 4 received an average of 12.8 (11...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1892/0891-6640(1999)013<0472:tgeoba>2.3.co;2
データ提供:米国国立医学図書館(NLM)
Aspirin, Carprofen, and Etodolac: A Gastroduodenal Odyssey in Canine Companions
Veterinary medicine is a vast and complex field, with a constant need for understanding the effects of various medications on our animal friends. This study, a veritable expedition into the canine gastrointestinal tract, examines the effects of buffered aspirin, carprofen, and etodolac on the gastroduodenal health of healthy dogs. The study employed a rigorous experimental design, dividing 24 dogs into four groups and closely monitoring them over 28 days. The findings provide crucial insights into the potential gastrointestinal effects of these medications, guiding veterinary practitioners in their decision-making.
Aspirin: A Potential Source of Gastroduodenal Distress
The study revealed that aspirin, a common pain reliever, was associated with the development of erosions and submucosal hemorrhages in the dogs. This finding suggests that aspirin should be administered with caution in dogs, especially those with pre-existing gastrointestinal conditions.
Healthy Paws, Healthy Choices
This research underscores the importance of responsible medication use in our furry companions. Just as we pay attention to our own health, it's vital to be aware of the potential side effects of medications, especially those that may impact the delicate balance of the gastrointestinal system.
Dr.Camel's Conclusion
This study provides valuable insights into the gastrointestinal impact of common medications in dogs. Much like navigating a desert landscape, understanding the potential risks and benefits of these drugs is crucial for ensuring the well-being of our canine friends.
Date :
- Date Completed 1999-11-23
- Date Revised 2019-05-13
Further Info :
Related Literature
English
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