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[Adjuvant systemic therapy of breast cancer--prognostic and predictive factors].

Author: RochlitzC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
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Overview

Additional treatment (adjuvant therapy) with Tamoxifen and/or chemotherapy after surgery for breast cancer has significantly reduced the risk of the cancer returning by 20-35%. However, further improvements are needed. New drugs, like taxanes, vinorelbine, and capecitabine, higher doses of chemotherapy for specific patients, immunotherapy using monoclonal antibodies, and gene therapy may help achieve this in the future. Researchers are also working to identify biological markers that can predict which patients will benefit most from a specific treatment, allowing for more targeted therapies and minimizing side effects for those who might not respond well.
Paper Details　
Original Abstract of the Article :
Adjuvant systemic treatment in breast cancer with Tamoxifen and/or chemotherapy has become a well-established standard of care during the last years. In adequately treated patients, a proportional reduction of the risk of recurrence of 20-35% can be achieved. Further improvement, however, is urgentl...See full text at original site
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引用元：
https://doi.org/10.1024/1023-9332.5.5.222

データ提供：米国国立医学図書館（NLM）

Adjuvant Systemic Therapy in Breast Cancer: A Search for the Perfect Route

Navigating the vast and intricate landscape of [breast cancer treatment] can be like traversing a treacherous desert. This research focuses on the role of adjuvant systemic therapies, such as Tamoxifen and chemotherapy, in improving the prognosis of breast cancer patients. The authors, like skilled desert navigators, are seeking the most effective routes to combat this formidable disease. They explore the potential benefits and challenges of various treatment modalities, highlighting the need for individualized approaches tailored to each patient's unique needs.

Personalized Medicine: Tailoring Treatment to the Individual

The key takeaway, like a rare oasis in the desert, is the importance of personalized medicine. Identifying predictive factors, or biological markers, that can predict an individual's response to treatment is a crucial step in optimizing care. This would allow us to personalize treatment regimens, potentially improving outcomes and reducing side effects. The numbers don't lie, a 20-35% reduction in recurrence risk is significant, and the authors are confident that further advancements in this field will lead to even greater strides.

Precision in Treatment: A Boon for Patients

The future of breast cancer treatment, like a mirage that gradually takes shape, is filled with promising advancements. The quest for personalized medicine, fueled by research like this, is a beacon of hope for patients. It promises a future where treatment is tailored to the individual, allowing us to effectively target the disease and minimize side effects. Ultimately, it's about finding the best path for each patient, a path that leads to a healthier and more fulfilling life.

Dr. Camel's Conclusion

Adjuvant systemic therapy is a crucial component in the battle against breast cancer. But as researchers, we're constantly striving for improvement, seeking to refine our strategies and personalize treatment based on each individual's unique biological landscape. This quest for precision medicine is like a desert bloom, a beacon of hope in the face of adversity.

Date :
  1. Date Completed 1999-11-18
  2. Date Revised 2019-11-03
Further Info :

Pubmed ID

10546521

DOI: Digital Object Identifier

10.1024/1023-9332.5.5.222

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Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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