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Tolerance and immunogenicity of the simultaneous administration of virosome hepatitis A and yellow fever vaccines.

Author: AlthausB, BovierP A, ChippauxA, GlueckR, LoutanL

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.

Overview

Simultaneous administration of an IRIV-HAV vaccine and a yellow fever vaccine (YFV) was found to be immunogenic, safe, and well-tolerated, with no cross-interference between the two vaccines.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The purpose of this study was to evaluate the tolerance and immunogenicity of a hepatitis A vaccine using immunopotentiating reconstituted influenza virosomes (IRIV) as adjuvant when administered simultaneously with a yellow fever vaccine (YFV). METHOD: An open prospective trial with tw...See full text at original site
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引用元：
https://doi.org/10.1111/j.1708-8305.1999.tb00523.x

データ提供：米国国立医学図書館（NLM）

A Harmonious Journey: Simultaneous Administration of Hepatitis A and Yellow Fever Vaccines

Vaccination is a vital tool for protecting individuals from infectious diseases, and the simultaneous administration of multiple vaccines can be a convenient and efficient approach. This study investigates the tolerance and immunogenicity of a hepatitis A vaccine, using immunopotentiating reconstituted influenza virosomes (IRIV) as an adjuvant, when administered simultaneously with a yellow fever vaccine (YFV). The authors seek to determine whether simultaneous administration impacts the effectiveness of each vaccine and the safety profile of the vaccination process.

A Symphony of Immunity: Simultaneous Vaccination and its Effects

The study demonstrates that simultaneous administration of the IRIV-HAV vaccine and the YFV vaccine is both safe and effective. The study participants developed adequate antibody responses to both antigens, suggesting that the simultaneous administration did not interfere with the effectiveness of either vaccine. This finding offers a valuable tool for public health initiatives, promoting the convenience and efficiency of vaccination programs.

Navigating the Desert of Infectious Diseases: Vaccination as a Protective Shield

This study highlights the importance of vaccination in protecting individuals from infectious diseases. It demonstrates that simultaneous administration of the IRIV-HAV and YFV vaccines can be a safe and effective approach, promoting convenience and efficiency. It underscores the crucial role of vaccination in public health, offering a powerful tool for preventing and controlling infectious diseases.

Dr. Camel's Conclusion

This study highlights the importance of vaccination in protecting individuals from infectious diseases. The study's findings demonstrate that simultaneous administration of the IRIV-HAV and YFV vaccines can be a safe and effective approach, offering a convenient and efficient way to boost immunity. This discovery is a testament to the ongoing efforts to improve vaccination practices, ensuring that individuals are protected from infectious diseases while maximizing the efficiency of public health programs.

Date :
  1. Date Completed 2000-01-19
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

10575170

DOI: Digital Object Identifier

10.1111/j.1708-8305.1999.tb00523.x

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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