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Omeprazole, clarithromycin and furazolidone for the eradication of Helicobacter pylori in patients with duodenal ulcer.

Author: CabralM M, DaniR, De CastroL P, DiasM G, FrancoJ M, MagalhãesL C, MendesG S, MoreiraL S, QueirozD M, RochaG A, SallesP G, ToppaN H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Clarithromycin and furazolidone in combination with omeprazole are a good alternative for Helicobacter pylori eradication in Brazilian patients with duodenal ulcer.
Paper Details　
Original Abstract of the Article :
AIM: To evaluate the efficacy of omeprazole plus clarithromycin and furazolidone in Helicobacter pylori eradication and duodenal ulcer healing in Brazilian patients. METHODS: Forty H. pylori-positive patients with duodenal ulcer were randomized to receive 20 mg omeprazole o.m. or b.d. for 1 month p...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2036.1999.00653.x

データ提供：米国国立医学図書館（NLM）

Eradicating Helicobacter pylori: A Trio of Drugs Shows Promise

Helicobacter pylori (H. pylori) is a common bacterium that can cause ulcers and other digestive problems. This study investigates the efficacy of a combination of omeprazole, clarithromycin, and furazolidone in eradicating H. pylori and healing duodenal ulcers in Brazilian patients.

The researchers conducted a randomized trial involving 40 patients with H. pylori-positive duodenal ulcers. The participants were treated with omeprazole, clarithromycin, and furazolidone for varying durations. The study found that the combination of these three drugs achieved a high eradication rate, with a success rate of 90% by intention-to-treat analysis and 97% by per protocol analysis.

A Powerful Trio for Stomach Health

This study suggests that this triple therapy regimen could be a valuable option for treating H. pylori infections and promoting ulcer healing. The high eradication rates achieved in this study are encouraging, potentially leading to improved patient outcomes and a reduction in the prevalence of H. pylori infections.

Fighting Stomach Troubles with a Trio of Drugs

This research is like a camel caravan carrying a valuable treasure – a combination of drugs that can effectively combat H. pylori infections.

Dr. Camel's Conclusion

This study is like a camel caravan carrying a precious cargo of healing – a combination of drugs that could effectively eradicate H. pylori and bring relief to those suffering from stomach problems.

Date :
  1. Date Completed 2000-02-10
  2. Date Revised 2019-08-31
Further Info :

Pubmed ID

10594400

DOI: Digital Object Identifier

10.1046/j.1365-2036.1999.00653.x

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Languages

English

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