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Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group.

Author: BonettiM, Castiglione-GertschM, CoatesA S, ColleoniM, CollinsJ, GelberR D, GoldhirschA, HolmbergS, LindtnerJ, MariniG, PriceK, RudenstamC M, ThürlimannB, VeronesiA

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

The study suggests that early initiation of adjuvant chemotherapy may improve outcome for premenopausal, node-positive breast cancer patients whose tumors do not express estrogen receptors (ER).
Paper Details　
Original Abstract of the Article :
The proper time to commence adjuvant chemotherapy after primary surgery for breast cancer is unknown. An analysis of the International (Ludwig) Breast Cancer Study Group (IBCSG) Trial V at a median follow-up of 11 years suggested that early initiation of adjuvant chemotherapy might improve outcome f...See full text at original site
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引用元：
https://doi.org/10.1200/JCO.2000.18.3.584

データ提供：米国国立医学図書館（NLM）

Timing is Everything: Early Adjuvant Chemotherapy for Breast Cancer

[Oncology] is a field where precision and timing are essential for successful treatment. This research investigates the impact of early initiation of adjuvant chemotherapy after primary surgery for breast cancer. The researchers analyzed data from the International Breast Cancer Study Group (IBCSG) Trial V to assess the relationship between timing of chemotherapy and treatment outcomes in premenopausal patients with estrogen receptor-negative breast cancer.

The Power of Early Intervention: Improved Outcomes for Breast Cancer

The study suggested that early initiation of adjuvant chemotherapy may improve outcomes for premenopausal breast cancer patients with tumors not expressing estrogen receptors. This finding underscores the importance of carefully considering the timing of chemotherapy initiation in breast cancer treatment and emphasizes the potential for improved outcomes with early intervention.

Navigating the Desert of Breast Cancer Treatment

Think of breast cancer treatment as a vast desert, with different therapies representing various oases offering potential relief. Timing is crucial in this desert, as each oasis holds a different significance at different stages of the journey. This research suggests that early initiation of chemotherapy can provide a crucial head start in this desert, increasing the chances of successful treatment and ultimately, survival.

Dr. Camel's Conclusion

The study suggests that early initiation of adjuvant chemotherapy may be beneficial for premenopausal breast cancer patients with tumors not expressing estrogen receptors. This research highlights the importance of timing in breast cancer treatment and underscores the potential for improved outcomes with early intervention.

Date :
  1. Date Completed 2000-02-29
  2. Date Revised 2022-04-15
Further Info :

Pubmed ID

10653873

DOI: Digital Object Identifier

10.1200/JCO.2000.18.3.584

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・Effective treatment of breast cancer
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PICO Info
in preparation
Languages

English

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