beta-agonistic bronchodilators: comparison of dose/response in working rat hearts.

Author: DahintenA, FitznerA, HalbigS, LibertusH, NollT, TreuschF, ZimmerG

Paper Details 
Original Abstract of the Article :
STUDY OBJECTIVES: Different beta-agonists are compared with regard to their cardiodepressive side effects. DESIGN: The metaphenolic bronchodilators reproterol, salbutamol, fenoterol, and terbutaline were introduced at a dosage of 0.0005 micromol to a maximum of 10 micromol per gram of heart tissue ...See full text at original site
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引用元:
https://doi.org/10.1378/chest.117.2.519

データ提供:米国国立医学図書館(NLM)

Beta-Agonistic Bronchodilators: Navigating the Desert of Respiratory Distress

Bronchodilators, like a cool breeze in the desert, help alleviate respiratory distress by opening up airways. This study delves into the world of beta-agonistic bronchodilators, exploring their effectiveness in treating asthma and their potential side effects on the heart.

This research team, like a caravan of explorers in the desert, carefully analyzed the effects of different beta-agonistic bronchodilators on the heart, noting their varying impacts on heart function and mitochondrial activity. The findings, like a well-stocked oasis, revealed that while some bronchodilators were beneficial, others had detrimental effects on the heart, particularly at higher doses.

Navigating the Desert of Bronchodilators: A Balancing Act

The study’s findings, like a compass guiding explorers through the desert, reveal the importance of understanding the delicate balance between the benefits and potential risks associated with certain bronchodilators. The research suggests that carefully selecting the right bronchodilator and managing the dose, akin to choosing the most suitable route in the desert, is crucial for optimizing treatment outcomes and minimizing potential side effects.

A Journey Through the Desert of Asthma: Balancing Relief and Risks

This study, like a refreshing spring in the desert, provides valuable insights into the world of beta-agonistic bronchodilators. It underscores the importance of open communication with a healthcare professional to determine the most appropriate bronchodilator and dose, ensuring that the benefits of relief outweigh potential risks.

Dr. Camel's Conclusion

This study, like a desert explorer navigating a complex terrain, reveals the importance of carefully choosing beta-agonistic bronchodilators to ensure optimal treatment outcomes and minimize potential side effects. The research highlights the delicate balance between relief and risks, like a caravan leader carefully selecting the best route in a vast desert.

Date :
  1. Date Completed 2000-03-03
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

10669699

DOI: Digital Object Identifier

10.1378/chest.117.2.519

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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