A randomized, controlled trial of high dose, inhaled budesonide versus oral prednisone in patients discharged from the emergency department following an acute asthma exacerbation.

Author: BaiT, FitzGeraldJ M, GrunfeldA, HaddonJ, JenningsB, KassenD, LeeJ, PareP, ShraggeD

Paper Details 
Original Abstract of the Article :
Prednisone (PRED) is recommended at discharge to reduce the relapse rate following emergency treatment for an asthmatic attack. However, PRED has systemic side effects. Inhaled anti-inflammatory medications, such as budesonide (BUD), are well tolerated. This study was designed to compare the effecti...See full text at original site
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引用元:
https://doi.org/10.1155/2000/587957

データ提供:米国国立医学図書館(NLM)

High-Dose Inhaled Budesonide vs. Oral Prednisone for Asthma Exacerbations

Asthma is a chronic respiratory condition that can lead to debilitating exacerbations. This research focuses on comparing the efficacy of high-dose inhaled budesonide (BUD) with oral prednisone (PRED) in reducing the relapse rate following emergency department treatment for acute asthma exacerbations. The authors conducted a randomized controlled trial, finding that high-dose inhaled BUD was as effective as PRED in preventing relapse. This study highlights the potential for inhaled corticosteroids to be a safer and more effective alternative to oral corticosteroids for managing asthma exacerbations.

Inhaled Corticosteroids: A Favorable Alternative

The study's findings demonstrate the potential for inhaled corticosteroids to be a valuable alternative to oral corticosteroids in managing asthma exacerbations. This approach offers the advantage of targeted delivery of the medication directly to the lungs, minimizing systemic side effects. It's like delivering water directly to the roots of a plant in the desert, maximizing efficiency and minimizing waste.

Improving Asthma Management

This research contributes to the ongoing efforts to improve asthma management and reduce the burden of this chronic condition. The findings suggest that high-dose inhaled BUD can be a valuable tool for clinicians managing asthma exacerbations, offering a safer and more effective alternative to oral corticosteroids. It's like finding a new watering hole in the desert, providing a vital resource for those battling the challenges of asthma.

Dr. Camel's Conclusion

This study underscores the importance of finding safe and effective treatment strategies for asthma exacerbations. The findings suggest that high-dose inhaled BUD can be a valuable alternative to oral corticosteroids, offering a more targeted approach to managing this challenging condition. This research is a reminder that the desert of asthma research is constantly evolving, with new discoveries emerging to improve patient outcomes.
Date :
  1. Date Completed 2000-05-04
  2. Date Revised 2018-05-25
Further Info :

Pubmed ID

10700672

DOI: Digital Object Identifier

10.1155/2000/587957

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Languages

English

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