False-positive tricyclic antidepressant drug screen results leading to the diagnosis of carbamazepine intoxication.

Author: BurnsM M, MatosM E, ShannonM W

Paper Details 
Original Abstract of the Article :
Ingestion of toxic substances is a common problem in pediatrics. When presented with the limited history of an unknown ingestion in a patient with altered mental status, a clinician depends on the physical examination and a toxic screen to determine the ingested substance(s). Some toxic screens yiel...See full text at original site
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引用元:
https://doi.org/10.1542/peds.105.5.e66

データ提供:米国国立医学図書館(NLM)

The Case of the Misleading Test: False-Positives in Drug Screening

The study explores the complexities of drug screening in the context of pediatric toxicology. It highlights the challenges associated with false-positive results in drug screens, particularly in cases of unknown ingestion. The study presents three cases where carbamazepine ingestion was initially missed due to false-positive tricyclic antidepressant results on the initial toxic screen. The study emphasizes the importance of understanding the limitations of drug screens and the potential for false-positive results.

The Deceptive Mirage: Understanding False-Positives in Drug Screening

The study reveals that false-positive results in drug screens can be a significant obstacle in the diagnosis and treatment of patients. The researchers highlight the importance of recognizing the limitations of drug screens and being aware of the various substances that can cause false-positive results. This research is like navigating a desert landscape where mirages can deceive the traveler, emphasizing the need for critical thinking and careful interpretation of test results.

Navigating the Shifting Sands: Avoiding Misdiagnosis in Drug Screening

The study underscores the importance of careful consideration of all available information, including the patient's history and clinical presentation, when interpreting drug screen results. The study highlights the need for clinicians to be aware of the potential for false-positive results and to utilize more reliable testing methods to confirm diagnoses. This research is like a camel caravan seeking to avoid the pitfalls of misdiagnosis, navigating the treacherous terrain of drug screening with caution and knowledge.

Dr.Camel's Conclusion

This study serves as a reminder of the importance of critical thinking and cautious interpretation when it comes to drug screening. It's like a wise camel guide warning us of the deceptive mirages that can arise in the desert of medical diagnosis. By understanding the limitations of drug screens and being aware of the potential for false-positives, we can navigate the path to accurate diagnosis and effective treatment.

Date :
  1. Date Completed 2000-05-18
  2. Date Revised 2019-05-16
Further Info :

Pubmed ID

10799630

DOI: Digital Object Identifier

10.1542/peds.105.5.e66

Related Literature

SNS
PICO Info
in preparation
Languages

English

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