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[The immunological basis of the administration of DTP-polio vaccine].

Author: CohenH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The DTP (whole cell)-polio vaccine is effective in providing immunity against diphtheria, tetanus, and polio. While the diphtheria and tetanus components have negligible side effects, the pertussis component can cause some side effects. Acellular pertussis vaccines, which are newer, have been shown to be as effective as the whole cell vaccine while causing fewer febrile reactions.
Paper Details　
Original Abstract of the Article :
The main subject of this essay is the analysis of the immunizing properties and possible side effects of DTP (whole cell)-polio vaccine, which since 1964 is the backbone of the immunization programme in the Netherlands. The concept, that the basis of the immunity conferred by diphtheria and tetanus ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11004905

データ提供：米国国立医学図書館（NLM）

Understanding the Immunological Basis of DTP-Polio Vaccine

This study delves into the intricacies of the DTP-polio vaccine, a cornerstone of immunization programs globally. The study examines the immunizing properties of the vaccine, focusing on the humoral immunity conferred by diphtheria and tetanus toxoids and inactivated poliovirus. The study also explores potential side effects, highlighting the negligible adverse reactions associated with diphtheria and tetanus toxoids and inactivated poliovirus, while acknowledging the greater risk of side effects associated with the pertussis component.

A Deep Dive into Vaccine Immunogenicity

This study provides valuable insights into the immunological mechanisms underlying the DTP-polio vaccine, highlighting the importance of humoral immunity in conferring protection against these diseases. The study's findings underscore the need for continued research to optimize the pertussis component of the vaccine, minimizing side effects while maintaining efficacy.

Navigating the Desert of Vaccine Development

This research, like a camel traversing a vast desert, journeys through the complexities of vaccine development, seeking to understand the intricate interplay between immunogenicity and safety. The study's findings provide valuable insights into the DTP-polio vaccine, highlighting the importance of ongoing research to ensure its effectiveness and safety.

Dr. Camel's Conclusion

This research provides a comprehensive overview of the immunizing properties and potential side effects of the DTP-polio vaccine. It highlights the importance of humoral immunity in conferring protection against diphtheria, tetanus, and polio, while emphasizing the need for continued research to optimize the pertussis component of the vaccine.

Date :
  1. Date Completed 2000-10-17
  2. Date Revised 2020-12-08
Further Info :

Pubmed ID

11004905

DOI: Digital Object Identifier

11004905

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・Side Effects of polio vaccine
SNS
PICO Info
in preparation
Languages

Dutch

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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