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Passive immunization for the prevention of otitis media.

Author: EnglundJ A, GlezenW P

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study reviewed the use of immunoglobulins for preventing otitis media. While human-derived polyclonal immunoglobulin has proven effective, it is expensive, difficult to administer, and associated with side effects. Monoclonal antibody has not been as successful. Maternal immunization with pneumococcal or Hib vaccines could potentially provide passive immunity to infants, but further research is needed.
Paper Details　
Original Abstract of the Article :
The safety and protective efficacy of exogenously-administered immunoglobulin for the prevention of otitis media has been demonstrated in the clinical trials of the human-derived polyclonal immune globulin used to prevent Haemophilus influenzae type b disease and respiratory syncytial virus infectio...See full text at original site
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引用元：
https://doi.org/10.1016/s0264-410x(00)00289-9

データ提供：米国国立医学図書館（NLM）

Passive Immunization: A Shield Against Otitis Media

Otitis media, an infection of the middle ear, is a common ailment that affects millions of children worldwide. This study explores the potential of passive immunization, a strategy that involves delivering pre-made antibodies, to prevent otitis media. Like a skilled camel, equipped with a protective coat against the harsh desert elements, researchers sought to create a shield against the bacteria and viruses that cause otitis media.

Maternal Immunization: A Promising Approach

The researchers focused on the potential of maternal immunization, a strategy that involves vaccinating mothers to transfer protective antibodies to their infants. They studied the effectiveness of pneumococcal and Hib vaccines in mothers, discovering that these vaccines could lead to significant levels of maternal-derived antibodies in infants. This finding, like a desert oasis providing much-needed water to weary travelers, offers a promising approach to preventing otitis media in infants.

Protecting Infants: A New Frontier in Otitis Media Prevention

This study highlights the potential of passive immunization, particularly maternal immunization, as a powerful tool in the fight against otitis media. The findings suggest that vaccinating mothers can provide infants with a crucial layer of protection against this common infection. Imagine a camel, sheltered by its mother's protective presence, now able to navigate the desert with greater confidence and security. This study offers a similar vision for infants, providing a potential path towards a healthier and more protected start to life.

Dr.Camel's Conclusion

This study explores the potential of passive immunization, particularly maternal immunization, to prevent otitis media in infants. The findings suggest that vaccinating mothers can transfer protective antibodies to their infants, offering a promising approach to reducing the incidence of this common infection. This research highlights the importance of preventive strategies in protecting infants from disease and underscores the ongoing quest for new and effective methods to safeguard their health.

Date :
  1. Date Completed 2001-07-05
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

11163474

DOI: Digital Object Identifier

10.1016/s0264-410x(00)00289-9

SNS
PICO Info
in preparation
Languages

English

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