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Treatment with interferon-alpha2b of naive non-cirrhotic patients with chronic hepatitis C according to viraemia and genotype. Results of a randomized multicentre study. The North West Italian Hepatological Group.
Author: , AndreoniM, ArrigoniA, BallaréM, CalleriG, CaritiG, CiancioA, Di NapoliA, GhisettiV, MaggiG, OraniA, PoggioA, RizzettoM, RoccaG, RoffiL, SaraccoG, SartoriM, TaboneM, TapperoG F, TerreniN, TraversoA
Original Abstract of the Article :
To establish whether tailoring the dosage of interferon (IFN)-alpha2b in non-cirrhotic naive patients with chronic hepatitis C according to hepatitis C virus (HCV) genotype and viraemic level improves the rate of sustained response (normal alanine aminotransferase values and HCV-RNA negativity 6 mon...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/00042737-200102000-00010
データ提供:米国国立医学図書館(NLM)
Tailoring Interferon Dosage for Hepatitis C
The field of [Hepatitis C treatment] is constantly evolving, and researchers are always searching for the best way to treat patients. This study investigates the effectiveness of tailoring interferon (IFN)-alpha2b dosage based on [HCV genotype and viral load] in patients with chronic hepatitis C. Researchers used a [randomized, multicenter study] to determine if this approach could improve the [rate of sustained response], which is defined as normal alanine aminotransferase values and HCV-RNA negativity six months after the end of therapy. The study found that [tailoring the interferon dosage based on genotype and viral load] did improve the rate of sustained response. This is an important finding, as it could help doctors to more effectively treat patients with chronic hepatitis C.
Personalized Treatment Approaches in Hepatitis C
This study emphasizes the importance of [personalized medicine] in the treatment of chronic hepatitis C. By taking into account the individual characteristics of each patient, doctors can tailor their treatment plans to achieve the best possible outcomes. This is especially important in the case of hepatitis C, as the virus can be very difficult to treat, and different patients respond differently to treatment.
Understanding the Impact of Genotype and Viral Load
The study also sheds light on the importance of [HCV genotype and viral load] in the effectiveness of treatment. These factors are crucial in determining the best course of treatment for each patient. It is essential for doctors to understand the specific characteristics of the virus in each patient to make informed decisions regarding treatment.
Dr. Camel's Conclusion
This study highlights the need for tailored treatment approaches in hepatitis C. Like a desert traveler adjusting their journey based on the shifting sands, we must adapt our treatment strategies to the individual characteristics of each patient. By considering factors like genotype and viral load, we can optimize treatment outcomes and improve the lives of those affected by this challenging disease.
Date :
- Date Completed 2001-05-10
- Date Revised 2019-09-06
Further Info :
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