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Prophylactic effect of citalopram in unipolar, recurrent depression: placebo-controlled study of maintenance therapy.

Author: AndersenM, HochstrasserB, IsaksenP M, KoponenH, LauritzenL, MahnertF A, NilR, PedersenS F, RouillonF, SwartJ C, WadeA G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Citalopram (20, 40, and 60 mg) is effective in preventing depressive recurrences in patients with recurrent unipolar major depression.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Major depression is highly recurrent. Antidepressant maintenance treatment has proven efficacy against recurrent depression. AIMS: Comparison of prophylactic efficacy of citalopram versus placebo in unipolar, recurrent depression. METHODS: Patients 18-65 years of age with recurrent uni...See full text at original site
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引用元：
https://doi.org/10.1192/bjp.178.4.304

データ提供：米国国立医学図書館（NLM）

Prophylactic Effect of Citalopram in Recurrent Depression

Depression is a pervasive mental health condition that can significantly impact an individual's quality of life. Recurrent depression, characterized by multiple episodes of depression, poses a significant challenge for both patients and healthcare providers. This study investigates the prophylactic efficacy of citalopram, a selective serotonin reuptake inhibitor (SSRI), in preventing depressive recurrences. The study employed a placebo-controlled design, randomizing patients with recurrent unipolar depression to receive either citalopram or a placebo. The results revealed a significant difference in time to recurrence, with patients receiving citalopram experiencing a longer period before experiencing another depressive episode. This discovery is like finding a hidden oasis in the desert of mental health, offering potential relief for individuals struggling with recurrent depression.

Citalopram: A Potential Solution for Recurrent Depression

The study's findings suggest that citalopram can play a significant role in preventing depressive recurrences, potentially offering a long-term solution for individuals with this challenging condition. The findings suggest that citalopram could be an effective tool for navigating the challenging terrain of recurrent depression.

Maintaining Mental Well-being

The study reinforces the importance of seeking professional help for mental health conditions. The findings suggest that individuals with recurrent depression can benefit from long-term treatment to prevent future episodes and maintain overall mental well-being.

Dr.Camel's Conclusion

This research offers a glimmer of hope in the vast desert of mental health research. The study's findings suggest that citalopram can be a valuable tool for preventing depressive recurrences, offering a potential lifeline for individuals struggling with this chronic condition. The study's implications are far-reaching, encouraging further research and personalized treatment strategies for those living with recurrent depression.

Date :
  1. Date Completed 2001-05-31
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

11282808

DOI: Digital Object Identifier

10.1192/bjp.178.4.304

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SNS
PICO Info
in preparation
Languages

English

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