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Original Abstract of the Article :
We evaluated the tolerability and toxicity attributed to pegylated liposomal doxorubicin (PL-DOX) in women with recurrent or refractory ovarian cancer, and reviewed procedures to prevent or treat toxicity induced by the agent. Medical records of 13 women who received PL-DOX between October 1997 and ...See full text at original site
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引用元:
https://doi.org/10.1592/phco.21.7.751.34572
データ提供:米国国立医学図書館(NLM)
Pegylated Liposomal Doxorubicin: Tolerability and Toxicity
This research delves into the field of chemotherapy and investigates the tolerability and toxicity of pegylated liposomal doxorubicin (PL-DOX) in women with recurrent or refractory ovarian cancer. The researchers reviewed the medical records of 13 women who received PL-DOX, aiming to assess the drug's side effects, toxicity management strategies, and factors influencing tolerability. Their main objective was to provide valuable insights for clinicians administering this chemotherapy drug.
The study found that PL-DOX, despite being simple to administer, presented challenges related to tolerability and toxicity management. Patients with more recent disease tolerated higher doses and more cycles of PL-DOX compared to those with long-standing disease. The study also documented various dose- or treatment-limiting complications, such as neutropenia, stomatitis, and plantar-palmar erythrodysesthesia. The researchers emphasized the importance of effective toxicity management strategies, including dosage reduction, treatment delays, and discontinuation, to mitigate adverse effects.
Navigating the Challenges of Chemotherapy: Insights from a Desert Journey
Chemotherapy, like a challenging desert journey, can come with its share of obstacles. This study offers valuable insights into the tolerability and toxicity of PL-DOX, a chemotherapy drug used for ovarian cancer. The research highlights the importance of individualizing treatment, managing toxicity effectively, and providing comprehensive support for patients undergoing chemotherapy.
Balancing Benefits and Risks: A Careful Approach to PL-DOX
This research, like a careful camel navigating the desert landscape, underscores the need for a balanced approach when using PL-DOX for ovarian cancer. While this drug holds potential benefits, it is essential to recognize and manage its potential side effects effectively. This study emphasizes the importance of individualized treatment plans, close monitoring, and proactive toxicity management to optimize patient outcomes.
Dr.Camel's Conclusion
This research, like a desert oasis offering respite from the challenges of chemotherapy, highlights the importance of understanding the tolerability and toxicity of PL-DOX. The study emphasizes the need for vigilant monitoring, individualized treatment plans, and effective toxicity management to maximize the benefits and minimize the risks of this chemotherapy drug.
Date :
- Date Completed 2001-12-04
- Date Revised 2019-09-15
Further Info :
Related Literature
English
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