Oral corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.

Author: GibsonP, WaltersE H, Wood-BakerR

Paper Details 
Original Abstract of the Article :
BACKGROUND: Systemic corticosteroids are widely used in the management of patients with acute exacerbations of COPD, in combination with other treatments. OBJECTIVES: To determine the effect of corticosteroids, administered either parenterally or orally, on the outcome in patients with acute exacer...See full text at original site
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引用元:
https://doi.org/10.1002/14651858.CD001288

データ提供:米国国立医学図書館(NLM)

Corticosteroids for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is a serious lung condition that can cause significant breathing difficulties. This research delves into the use of corticosteroids, a type of medication often used to manage inflammation, in the treatment of acute exacerbations of COPD, which are sudden worsening of symptoms.

The study aims to assess the effectiveness of corticosteroids, administered either parenterally (injection) or orally, in treating acute COPD exacerbations. The authors conducted a systematic review of randomized controlled trials comparing corticosteroid treatment to a placebo, while also considering other standard treatments like bronchodilators and antibiotics.

The results of the review indicate that corticosteroid treatment is beneficial in improving lung function, specifically the forced expiratory volume in one second (FEV1), within the first 72 hours after treatment. However, the study also reveals a higher risk of adverse drug reactions with corticosteroid therapy. While corticosteroids show promise in managing acute exacerbations of COPD, careful consideration must be given to the potential side effects and their long-term implications.

Corticosteroids: Potential Benefits and Risks

The study reveals that corticosteroids can be effective in improving lung function in the initial stages of an acute COPD exacerbation. However, it's crucial to be aware of the associated risk of adverse drug reactions. The study highlights the importance of weighing the potential benefits against the potential risks when considering corticosteroid treatment for COPD.

Living with COPD: A Balancing Act

If you live with COPD, it's essential to consult with your healthcare provider about the best management strategies. The study emphasizes the importance of understanding the nuances of corticosteroid treatment, including its potential benefits and risks, to make informed decisions about your healthcare journey.

Dr.Camel's Conclusion

Imagine a desert windstorm, swirling and choking, making it difficult to breathe. Acute exacerbations of COPD can be like that, making it hard to catch your breath. This study sheds light on the use of corticosteroids as a potential tool for managing these windstorms, but it's important to remember that even the most potent desert medicine can come with side effects. A thorough understanding of your condition and the treatment options is crucial.

Date :
  1. Date Completed 2002-02-28
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

11405984

DOI: Digital Object Identifier

10.1002/14651858.CD001288

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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