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Post-operative GnRH analogue treatment after conservative surgery for symptomatic endometriosis stage III-IV: a randomized controlled trial.
Author: BianchiS, BusaccaM, CaliaC, CandianiM, De MarinisS, SomiglianaE, VignaliM
Original Abstract of the Article :
BACKGROUND: In order to decrease endometriosis recurrence after surgical therapy, it has been proposed to use a post-surgical oestrogen-lowering medical treatment. Results from previous trials on this topic are contradictory. METHODS: A total of 89 women were randomized, by computer-generated list,...See full text at original site
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引用元:
https://doi.org/10.1093/humrep/16.11.2399
データ提供:米国国立医学図書館(NLM)
Post-Operative GnRH Analogue Treatment: A Randomized Controlled Trial
This research delves into the realm of gynecology, specifically focusing on the treatment of endometriosis, a condition where tissue similar to the uterine lining grows outside the uterus. It's like a misplaced oasis in the desert, causing havoc with a woman's reproductive system. This study aimed to determine the effectiveness of a post-operative GnRH analogue treatment, which acts like a desert wind, suppressing estrogen levels, for women with stage III-IV endometriosis. The researchers conducted a randomized controlled trial, comparing the treatment group to a group receiving expectant management. They discovered that this treatment had no significant impact on pain reduction, fertility, or disease recurrence. It seems like the treatment's effect was akin to a gentle breeze, unable to shift the sands of endometriosis.GnRH Analogues: No Clear Benefit for Endometriosis
The study revealed that after conservative surgery for stage III-IV endometriosis, a 3-month course of GnRH analogue treatment doesn't significantly improve pain reduction, fertility, or disease recurrence. The researchers observed similar outcomes between the treatment group and the control group, suggesting that the treatment may not offer any significant benefit for these women. It's like finding a mirage in the desert, an illusion of hope that ultimately fades away.Navigating Endometriosis: What to Know
Based on this study, it's important to understand that a 3-month course of GnRH analogue treatment may not be the magical cure for endometriosis. While surgery is a common first step, it seems that other treatment strategies, like lifestyle changes, may be more effective. It's crucial to consult with a doctor for personalized advice based on the individual's specific needs and circumstances. It's like finding your way through the desert, taking each step carefully and seeking guidance from an experienced guide.Dr.Camel's Conclusion
This study sheds light on the potential limitations of GnRH analogue treatment for endometriosis. It emphasizes the need for further research to identify more effective treatment options and develop personalized strategies that address the unique challenges faced by women with this condition. Just like finding the perfect route across a vast desert, finding the right treatment for endometriosis requires careful consideration and exploration of different approaches.Date :
- Date Completed 2002-01-11
- Date Revised 2019-05-13
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