Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.

Author: MarsonA G, Tudur SmithC, WilliamsonP R

Paper Details 
Original Abstract of the Article :
Phenytoin and valproate are commonly used antiepileptic drugs. It is generally believed that phenytoin is more effective for partial onset (simple partial, complex partial and secondary generalized tonic-clonic seizures) seizures whilst valproate is more effective in generalized onset seizures (gene...See full text at original site
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引用元:
https://doi.org/10.1002/14651858.CD001769

データ提供:米国国立医学図書館(NLM)

Navigating the Labyrinth of Epilepsy Treatment: A Head-to-Head Comparison of Phenytoin and Valproate

This research navigates the complex world of epilepsy treatment, comparing the effectiveness of two commonly used antiepileptic drugs: phenytoin and valproate. The study, using individual patient data meta-analysis, aimed to determine which drug is more effective for treating different types of seizures. The researchers found that phenytoin is generally considered more effective for partial onset seizures, while valproate is often preferred for generalized onset seizures. However, the study also highlighted the need for individualized treatment approaches, considering the unique needs of each patient and the specific type of seizure they experience.

A Desert Compass for Epilepsy Treatment: Choosing the Right Path

This study provides valuable insights for clinicians treating epilepsy. The findings suggest that phenytoin may be a better choice for partial onset seizures, while valproate could be more effective for generalized onset seizures. However, individual patient characteristics and seizure type should be carefully considered when selecting an antiepileptic drug.

A Desert Oasis of Knowledge: Understanding Epilepsy Treatment

This research highlights the importance of a personalized approach to epilepsy treatment. By understanding the specific type of seizure and individual patient factors, clinicians can choose the most appropriate antiepileptic drug and optimize treatment outcomes.

Dr.Camel's Conclusion

This study provides valuable guidance for navigating the complex world of epilepsy treatment. By understanding the unique characteristics of different seizure types and individual patient needs, clinicians can choose the most appropriate antiepileptic drug and ensure the best possible outcomes for their patients.
Date :
  1. Date Completed 2002-04-19
  2. Date Revised 2018-12-21
Further Info :

Pubmed ID

11687121

DOI: Digital Object Identifier

10.1002/14651858.CD001769

Related Literature

SNS
PICO Info
in preparation
Languages

English

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