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Testosterone dose-response relationships in healthy young men.

Author: BermanN, BhasinD, BhasinS, BrossR, CasaburiR, ChenX, DzekovC, DzekovJ, MaglianoL, PhillipsJ, ShenR, SinghA B, Sinha-HikimI, StorerT W, WoodhouseL, YarasheskiK E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study found that testosterone effects are dose-dependent and that changes in fat-free mass, muscle size, strength, and power are positively correlated with testosterone concentrations.
Paper Details　
Original Abstract of the Article :
Testosterone increases muscle mass and strength and regulates other physiological processes, but we do not know whether testosterone effects are dose dependent and whether dose requirements for maintaining various androgen-dependent processes are similar. To determine the effects of graded doses of ...See full text at original site
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引用元：
https://doi.org/10.1152/ajpendo.2001.281.6.E1172

データ提供：米国国立医学図書館（NLM）

Testosterone: A Desert Oasis for Muscle Growth

Testosterone, a crucial hormone for male development and health, plays a vital role in muscle growth, strength, and other physiological processes. This study delves into the world of endocrinology, specifically examining the dose-response relationships of testosterone in healthy young men.

The researchers investigated the effects of graded doses of testosterone on various physiological parameters, including body composition, muscle size, strength, power, sexual and cognitive functions, prostate-specific antigen (PSA), plasma lipids, hemoglobin, and insulin-like growth factor I (IGF-I) levels. They aimed to understand how different doses of testosterone impacted these parameters and to determine if there were dose-dependent relationships.

The Effects of Testosterone: A Dose-Dependent Journey

The study found that testosterone had dose-dependent effects on various parameters. Increases in fat-free mass, muscle size, strength, and power were positively correlated with testosterone levels, suggesting a clear dose-response relationship. However, the study also highlighted that different androgen-dependent processes had different testosterone dose-response relationships, suggesting that specific parameters may be more sensitive to testosterone levels than others.

Navigating the Desert of Testosterone Levels: Balancing Health and Performance

Testosterone is a powerful hormone that can impact various aspects of health and performance. This study emphasizes the importance of understanding the dose-dependent effects of testosterone and the need for careful monitoring and management to ensure optimal health outcomes. Consulting with a healthcare professional is crucial for navigating the complex landscape of testosterone levels and achieving a healthy balance.

Dr.Camel's Conclusion

Testosterone, a vital oasis in the desert of male health, plays a significant role in muscle growth and strength. This study provides insights into the dose-dependent effects of testosterone, highlighting the importance of finding the right balance for optimal health and performance. Like a camel navigating the vast desert, understanding the nuances of testosterone levels is key to maintaining a healthy journey.

Date :
  1. Date Completed 2002-01-03
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

11701431

DOI: Digital Object Identifier

10.1152/ajpendo.2001.281.6.E1172

SNS
PICO Info
in preparation
Languages

English

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