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Treatment of established postoperative nausea and vomiting: a quantitative systematic review.

Author: HenziIris, Kazemi-KjellbergFaranak, TramèrMartin R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This systematic review found that 5-HT3 receptor antagonists are effective in preventing further vomiting in postoperative nausea and vomiting patients, with a 20%-30% absolute risk reduction compared to placebo.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The relative efficacy of antiemetics for the treatment of postoperative nausea and vomiting (PONV) is poorly understood. METHODS: Systematic search (MEDLINE, Embase, Cochrane Library, bibliographies, any language, to 8.2000) for randomised comparisons of antiemetics with any comparator f...See full text at original site
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引用元：
https://doi.org/10.1186/1471-2253-1-2

データ提供：米国国立医学図書館（NLM）

Treating Postoperative Nausea and Vomiting: A Comprehensive Review

The field of [anesthesiology] is constantly seeking ways to improve patient comfort and recovery after surgery. This systematic review examines the efficacy of various antiemetics in treating postoperative nausea and vomiting (PONV) that occurs after initial treatment. The review analyzed data from 18 randomized controlled trials comparing different antiemetics to placebo in treating established PONV. The review found that 5-HT3 receptor antagonists, including dolasetron, granisetron, tropisetron, and ondansetron, were effective in reducing vomiting, with absolute risk reductions of 20-30% compared to placebo.

A Guide to Managing Postoperative Nausea

The review's findings provide valuable guidance for managing established PONV. The effectiveness of 5-HT3 receptor antagonists in reducing vomiting offers a potential solution for patients experiencing this common postoperative complication.

A Smoother Recovery Journey

This review sheds light on effective treatments for PONV, which can make the recovery journey smoother for patients. It's like discovering a cool oasis in the desert of postoperative discomfort, offering relief from nausea and vomiting.

Dr.Camel's Conclusion

This systematic review provides a comprehensive overview of the current evidence on treating established PONV. It highlights the effectiveness of 5-HT3 receptor antagonists and underscores the need for further research to optimize treatment strategies for this common postoperative complication.
Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

11734064

DOI: Digital Object Identifier

10.1186/1471-2253-1-2

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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