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Topical tacrolimus (FK506) and mometasone furoate in treatment of dyshidrotic palmar eczema: a randomized, observer-blinded trial.

Author: AbeckDietrich, MöhrenschlagerMatthias, RemlingRoland, RingJohannes, SchnoppChristina, WeiglLorenz

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Tacrolimus 0.1% ointment and mometasone furoate 0.1% ointment both reduced dyshidrotic eczema symptoms in palmar areas after 2 weeks, but tacrolimus was less effective long-term.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Dyshidrotic palmoplantar eczema is a frequent disease often running a chronic relapsing course. Topical glucocorticosteroids form the mainstay of therapy, and alternatives are urgently warranted. OBJECTIVE: This study was performed to compare the efficacy of tacrolimus (FK506) 0.1% oint...See full text at original site
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引用元：
https://doi.org/10.1067/mjd.2002.117856

データ提供：米国国立医学図書館（NLM）

Treating Dyshidrotic Palmoplantar Eczema: A Desert Oasis of Relief

The study of dermatology is a voyage through the skin's intricate layers and the diverse conditions that can affect it. This research investigates the effectiveness of topical tacrolimus (FK506) and mometasone furoate in treating dyshidrotic palmoplantar eczema, a chronic and often frustrating skin condition.

Topical Treatments: A Desert Oasis of Hope

The study found that both tacrolimus and mometasone furoate were effective in reducing the severity of dyshidrotic eczema. While both treatments showed initial improvement, tacrolimus was associated with a rebound in symptoms after treatment cessation. The researchers suggest that tacrolimus may be beneficial in combination with mometasone furoate for long-term management of this chronic condition.

Managing Dyshidrotic Eczema: Finding the Right Treatment Path

This research provides valuable insights into the treatment options for dyshidrotic eczema. The findings suggest that tacrolimus and mometasone furoate can offer effective relief, but careful consideration should be given to long-term management strategies to minimize the risk of symptom rebound.

Dr.Camel's Conclusion

This research highlights the importance of finding the right treatment approach for chronic skin conditions like dyshidrotic eczema. Like a camel seeking the most efficient route across the desert, dermatologists must navigate a variety of treatment options to provide optimal care for their patients.

Date :
  1. Date Completed 2002-02-12
  2. Date Revised 2019-07-09
Further Info :

Pubmed ID

11756949

DOI: Digital Object Identifier

10.1067/mjd.2002.117856

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・Effective treatment of eczema
SNS
PICO Info
in preparation
Languages

English

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