Paper Details 
Original Abstract of the Article :
This single-blind crossover trial compared the effects of single oral doses of two antacids on esophageal and gastric pH in subjects with heartburn. Gastric and esophageal pH were assessed in 83 subjects from 1 h before to 4 h after a refluxogenic meal. Subjects received two chewable tablets of a hi...See full text at original site
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引用元:
https://doi.org/10.1097/00045391-199508000-00006

データ提供:米国国立医学図書館(NLM)

Antacids for Heartburn: Comparing Aluminum/Magnesium Hydroxide and Calcium Carbonate

In the realm of [gastrointestinal medicine], [heartburn], a common symptom of [gastroesophageal reflux disease (GERD)], can significantly impact [quality of life]. This research delves into the comparative efficacy of two commonly used [antacids], [aluminum/magnesium hydroxide] and [calcium carbonate], in managing [heartburn] by assessing their impact on [esophageal] and [gastric pH]. This study aims to provide a direct comparison of these two antacids based on their [onset of action], [duration of action], and overall impact on [pH levels] in the [esophagus] and [stomach].

Aluminum/Magnesium Hydroxide: A More Effective Antacid for Heartburn

The researchers found that both [antacids] significantly increased [esophageal pH] compared to [placebo]. However, [aluminum/magnesium hydroxide] demonstrated a faster [onset of action] and a longer [duration of action] compared to [calcium carbonate]. Additionally, [aluminum/magnesium hydroxide] was the only [antacid] to significantly increase [gastric pH] compared to [placebo]. This study suggests that [aluminum/magnesium hydroxide] may be a more effective option for [heartburn] relief.

Choosing the Right Antacid for Heartburn: Consider Duration of Action

This research, like a guidebook for navigating the desert of [heartburn], offers valuable insights into the choice of [antacids]. The findings highlight the importance of considering the [duration of action] of different [antacids] in selecting the most effective treatment for [heartburn]. This study underscores the importance of understanding the individual needs of patients and choosing the most appropriate [antacid] based on their specific [symptoms] and [treatment goals].

Dr. Camel's Conclusion

This study, like a well-stocked oasis in the desert of [heartburn], provides valuable insights into the comparative efficacy of two common [antacids]. The findings suggest that [aluminum/magnesium hydroxide] may be a more effective option due to its faster [onset of action] and longer [duration of action]. This research highlights the importance of understanding the nuances of [antacid] action to optimize [treatment outcomes] for patients with [heartburn].

Date :
  1. Date Completed n.d.
  2. Date Revised 2019-11-20
Further Info :

Pubmed ID

11854825

DOI: Digital Object Identifier

10.1097/00045391-199508000-00006

Related Literature

SNS
PICO Info
in preparation
Languages

English

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