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Ketorolac, diclofenac, and ketoprofen are equally safe for pain relief after major surgery.

Author: , AbdallaM, BianchiPorro G, BonnetF, CamuF, EbrahimS, EscolarG, ForrestJ B, GreerI A, HeitlingerE, JageJ, KehletH, LangmanM J S, PocockS, SamamaM M, VeloG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compares the risk of serious adverse effects with ketorolac versus diclofenac or ketoprofen in adult patients after elective major surgery.
Paper Details　
Original Abstract of the Article :
Ketorolac is approved for the relief of postoperative pain but concerns have been raised over a possible risk of serious adverse effects and death. Two regulatory reviews in Europe on the safety of ketorolac found the data were inconclusive and lacked comparison with other non-steroidal anti-inflamm...See full text at original site
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引用元：
https://doi.org/10.1093/bja/88.2.227

データ提供：米国国立医学図書館（NLM）

Ketorolac, Diclofenac, and Ketoprofen: A Comparative Study of Postoperative Pain Relief

In the field of [anesthesiology], [postoperative pain management] is a critical aspect of patient care. This study investigates the safety and efficacy of [ketorolac] compared to [diclofenac and ketoprofen] in relieving pain after major surgery. Think of this as a desert explorer comparing different methods of navigating a challenging terrain, seeking the safest and most effective route.

Equal Safety and Efficacy: A Comparative Analysis

The study found that [ketorolac, diclofenac, and ketoprofen] were all equally safe and effective in relieving postoperative pain. This finding provides valuable information for clinicians, allowing them to confidently choose from these three pain relievers based on individual patient needs and preferences. It's like having three reliable camels in the desert, each capable of carrying you safely to your destination, offering different strengths and advantages.

Navigating Postoperative Pain Relief

This study provides valuable insights into the safety and efficacy of different non-steroidal anti-inflammatory drugs for postoperative pain relief. It offers clinicians valuable information to guide their treatment decisions, ensuring optimal pain management for their patients. This knowledge is like a well-worn map in the desert, guiding travelers safely across the terrain, avoiding the dangers and maximizing their comfort.

Dr. Camel's Conclusion

This study provides reassuring data on the safety and efficacy of ketorolac, diclofenac, and ketoprofen for postoperative pain relief. It's a reminder that in the field of pain management, there is often a variety of options available, each with its own strengths and weaknesses. As a wise traveler in the desert, we must carefully consider our choices, selecting the best tool for the journey ahead.

Date :
  1. Date Completed 2002-04-04
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

11883386

DOI: Digital Object Identifier

10.1093/bja/88.2.227

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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