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Nursing considerations for managing topotecan-related hematologic side effects.

Author: AnastasiaP J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study discusses the use of topotecan in relapsed ovarian cancer and platinum-sensitive small-cell lung cancer. Hematologic toxicity is the predominant side effect, which can be managed by identifying high-risk patients and adjusting the dose.
Paper Details　
Original Abstract of the Article :
Topotecan (Hycamtin, SmithKline Beecham, Philadelphia, PA) was approved by the U.S. Food and Drug Administration in 1996 for use in relapsed ovarian cancer and in 1999 for platinum-sensitive small-cell lung cancer. Hematologic toxicity has been the predominant side effect associated with its use. Pa...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/11899407

データ提供：米国国立医学図書館（NLM）

Navigating the Terrain of Topotecan Side Effects: A Guide for Nurses

Topotecan is a chemotherapy drug used to treat certain types of cancer. While it can be effective in treating cancer, it can also cause significant side effects, particularly hematologic toxicity, which affects the blood cells. This research provides practical guidance for nurses on managing these side effects.

Charting the Course: Identifying High-Risk Patients and Managing Side Effects

The study emphasizes the importance of identifying high-risk patients who are more likely to experience severe hematologic toxicity. The authors recommend dose modifications based on creatinine clearance measurements to minimize the risk of these side effects. By adjusting the dosage, nurses can help patients manage the effects of topotecan without compromising its effectiveness.

Keeping on Track: Minimizing Side Effects and Optimizing Treatment

This research provides essential information for nurses caring for patients receiving topotecan. By understanding the risks and implementing appropriate strategies, nurses can help patients navigate the challenges of chemotherapy and optimize their treatment outcomes. It's like a skilled guide leading a caravan through the desert, ensuring that the journey is safe and effective.

Dr. Camel's Conclusion

Just as a camel guides its caravan through a challenging desert landscape, nurses play a crucial role in guiding patients through the complex terrain of chemotherapy side effects. This research provides valuable insights and practical strategies for nurses to manage topotecan-related hematologic toxicity, ensuring a smoother and more successful journey for patients.

Date :
  1. Date Completed 2002-05-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

11899407

DOI: Digital Object Identifier

11899407

Related Literature

Article Analysis
・Side Effects of topotecan
SNS
PICO Info
in preparation
Languages

English

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