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Randomized placebo-controlled trial of metronidazole 1% cream with sunscreen SPF 15 in treatment of rosacea.
Author: ChinD A, GirardC, JeandupeuxD, KrolA, MurrayH E, PappK A, PoulinY, TanJ K L
Original Abstract of the Article :
BACKGROUND: Rosacea is a photoaggravated dermatosis responsive to treatment with topical and oral antibiotics. A formulation combining metronidazole 1% cream with sunscreen SPF 15 was developed for the treatment of rosacea. OBJECTIVE: The objective of this study was to determine the safety and effi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1007/s10227-001-0144-4
データ提供:米国国立医学図書館(NLM)
A Topical Solution for Rosacea
Rosacea is a common skin condition that causes redness, bumps, and pimples, often triggered by sun exposure. This research investigates the effectiveness of a topical cream combining metronidazole with sunscreen SPF 15 in treating moderate to severe rosacea. The study utilized a randomized, placebo-controlled, double-blind design, involving 120 patients who applied the cream twice daily for 12 weeks. The researchers discovered that the cream significantly improved inflammatory lesions, redness, and blood vessel visibility compared to placebo. Importantly, the cream was well-tolerated, with only mild and reversible side effects. This study provides strong evidence that this combined formulation offers an effective and safe treatment option for individuals struggling with rosacea.
A Promising Treatment for Rosacea
The findings of this study suggest that a topical cream containing metronidazole and sunscreen SPF 15 can be a valuable treatment for moderate to severe rosacea. The significant improvement in inflammatory lesions, redness, and blood vessel visibility observed in the treatment group highlights the potential benefits of this combined approach.
Sun Protection: A Key Component
This research emphasizes the crucial role of sun protection in managing rosacea. The inclusion of sunscreen SPF 15 in the treatment cream offers a convenient way to protect the skin from sun damage, which is a known trigger for rosacea flare-ups. This highlights the importance of sun avoidance and the use of broad-spectrum sunscreen in daily skincare routines, especially for those prone to rosacea.
Dr. Camel's Conclusion
Rosacea is a challenging skin condition, often leaving individuals feeling self-conscious and frustrated. This research provides a beacon of hope, showcasing a topical treatment that effectively addresses the key symptoms. The combination of metronidazole and sunscreen SPF 15 offers a dual-action approach that targets both inflammation and sun sensitivity, two crucial factors in managing rosacea. This study reinforces the importance of sun protection in skincare, reminding us that taking preventive measures can significantly impact our skin health.
Date :
- Date Completed 2003-04-15
- Date Revised 2019-11-05
Further Info :
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