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Effects of fluticasone propionate in COPD patients with bronchial hyperresponsiveness.

Author: BogaardJ M, HegmansJ P J J, HoogstedenH C, MulderP G H, PrinsJ-B, VerhoevenG T

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Inhaled corticosteroids may not be as effective for chronic obstructive pulmonary disease (COPD) as they are for asthma. Only certain groups of COPD patients benefit from steroid treatment. A study examined the effects of inhaled fluticasone propionate (FP) on lung function and inflammation in COPD patients with bronchial hyperresponsiveness (BHR).
Paper Details　
Original Abstract of the Article :
Treatment of chronic obstructive pulmonary disease (COPD) with inhaled corticosteroids does not appear to be as effective as similar treatment of asthma. It seems that only certain subgroups of patients with COPD benefit from steroid treatment. A study was undertaken to examine whether inhaled fluti...See full text at original site
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引用元：
https://doi.org/10.1136/thorax.57.8.694

データ提供：米国国立医学図書館（NLM）

Fluticasone Propionate for COPD: A Targeted Approach to Treatment

The study of [chronic obstructive pulmonary disease (COPD)] is a quest for effective treatments that can improve the quality of life for individuals struggling with this debilitating lung condition. While [inhaled corticosteroids] have proven effective in treating asthma, their efficacy in COPD has been less clear. This study investigates the effects of inhaled fluticasone propionate (FP) in a specific subgroup of COPD patients—those with [bronchial hyperresponsiveness (BHR)].

Seeking Precision in Treatment: Fluticasone Propionate and Bronchial Hyperresponsiveness

The researchers found that inhaled FP had a positive impact on lung function and markers of inflammation in COPD patients with BHR. This suggests that a targeted approach, focusing on specific subgroups of COPD patients, may hold the key to more effective treatment outcomes.

A Tailored Approach to COPD Management: Identifying Subgroups for Targeted Therapies

This study underscores the importance of identifying specific subgroups of COPD patients who may benefit most from inhaled corticosteroids. This personalized approach to treatment can help maximize the benefits of medication while minimizing potential side effects.

Dr.Camel's Conclusion

Just as a desert traveler navigates different terrains with varying strategies, COPD treatment requires a tailored approach. This study highlights the importance of recognizing the unique characteristics of COPD patients and adapting treatment accordingly. By understanding the nuances of this complex disease, we can better guide individuals towards a path of improved health and well-being.

Date :
  1. Date Completed 2002-09-12
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

12149529

DOI: Digital Object Identifier

10.1136/thorax.57.8.694

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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