Dexamethasone in combination with dolasetron for prophylaxis in the ambulatory setting: effect on outcome after laparoscopic cholecystectomy.

Author: BerrisfordSally B, ColomaMargarita, MacalusoAmy R, MarkowitzScott D, ThorntonKevin C, WhitePaul F, WhittenCharles W

Paper Details 
Original Abstract of the Article :
Postoperative nausea and vomiting after laparoscopic cholecystectomy remains a common problem despite routine antiemetic prophylaxis. Therefore, the authors investigated the effect of administering 4 mg intravenous dexamethasone as an adjunct to a 5-HT3 antagonist (12.5 mg intravenous dolasetron) wi...See full text at original site
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引用元:
https://doi.org/10.1097/00000542-200206000-00013

データ提供:米国国立医学図書館(NLM)

Combating Postoperative Nausea and Vomiting

This research investigates the effectiveness of combining dexamethasone with dolasetron for prophylaxis against postoperative nausea and vomiting (PONV) following laparoscopic cholecystectomy. The researchers administered 4 mg intravenous dexamethasone as an adjunct to 12.5 mg intravenous dolasetron, a 5-HT3 antagonist, to patients undergoing laparoscopic cholecystectomy. The study aimed to evaluate the impact of this combined approach on patient outcome, specifically focusing on reducing the incidence of PONV.

A New Strategy for PONV Prevention

The study's findings suggest that combining dexamethasone with dolasetron may be an effective strategy for preventing PONV after laparoscopic cholecystectomy. The researchers observed a significant reduction in PONV incidence in patients receiving this combined approach, highlighting its potential as a valuable tool for improving patient comfort and recovery after surgery. The study encourages further investigation into this combination therapy in larger patient populations and diverse surgical settings.

Improving Patient Recovery: A Focus on Comfort

This research underscores the importance of minimizing discomfort and improving patient recovery after surgery. The study's findings highlight the potential of combining dexamethasone with dolasetron to effectively prevent PONV, a common and often distressing complication. The research encourages a focus on patient comfort and well-being, emphasizing the need for effective strategies to manage postoperative complications and promote a smoother recovery experience.

Dr.Camel's Conclusion

This study delves into the challenges of managing postoperative nausea and vomiting (PONV), a common and often debilitating complication following surgery. The researchers demonstrate the potential of combining dexamethasone with dolasetron to effectively prevent PONV, improving patient comfort and accelerating recovery. Just as the desert's harsh environment requires resilience and adaptation, so too does surgery necessitate strategies to manage pain and discomfort. This research provides valuable insights into the potential of combined therapies to enhance patient outcomes and promote a more comfortable recovery experience.

Date :
  1. Date Completed 2002-08-27
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

12170046

DOI: Digital Object Identifier

10.1097/00000542-200206000-00013

Related Literature

SNS
PICO Info
in preparation
Languages

English

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